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    Home > Active Ingredient News > Immunology News > Multiple articles read the many benefits of fish oil for the health of the body!

    Multiple articles read the many benefits of fish oil for the health of the body!

    • Last Update: 2020-08-01
    • Source: Internet
    • Author: User
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    this article, the small compilation of a number of research results, together focus on the fish oil on the body's health benefits, share to everyone!
    Picture Source: The Conversation

    . 1.
    BMJ: More than 400,000 people followed the results of 13 years Fish oil supplements or directly related to the overall mortality and decreased risk of cardiovascular disease death!

    : 10.1136/bmj.m456

    , scientists from southern medical universities and other institutions found that regular intake of supplements or reduced the risk of death and cardiovascular events, such as heart attacks and
    stroke
    s,

    , found that regular intake of supplements can reduce the risk of death and cardiovascular events, such as heart attacks and
    strokes;

    fish oil is the most popular dietary supplement in the UK and other developed countries, and there is research evidence that omega-3 fatty acids in fish oil can help prevent cardiovascular disease and reduce mortality, but researchers still lack clear evidence; to shed more into the link, researchers analyzed data from the
    of the Biosample Bank from the UK
    , which included 427,678 men and women aged 40-69 between 2006 and 2010.

    2.
    Circulation: Fish oil or "god medicine" for heart failure

    doi: 10.1161/CIRCULATIONAHA.119.044645

    recently published in the international journal Circulation In the study, scientists from the Bregan Women's Hospital and Harvard Medical School found that fish oil may be effective in treating heart failure,
    a
    clinical trial that analyzed the effects of fish oil and vitamin D on heart disease and cancer risk in people.

    researchers say the main trials (VITAL, Vitamin D and Omega-3 Trial) have yielded some encouraging results, giving older people fish oil supplements to reduce their risk of heart attack in the next few years, especially for people who never consume fish oil. The impact of the risk of heart failure and hospitalization, heart failure is a chronic disease in which the heart fails to pump blood effectively into the body, often due to heart muscle damage caused by a heart attack, so researchers wonder whether the benefits observed in
    clinical trials
    extend to heart failure patients.


    EJN: How can we better absorb fish oil to get the most out of it?

    doi: 10.1007/s00394-019-02118-x

    Fish oil is one of the most common dietary supplements in the world and has a wide range of health benefits, such as helping to lower cholesterol levels and arteriosclerosis, improve mental health, help
    weight loss
    , improve eye and skin health, and relieve arthritis symptoms, but fish oil is best absorbed by the body when ingested with a high-fat diet, so those who take fish oil supplements while maintaining a healthy diet may not be able to get the best health benefits from their daily intake of fish oil. In a recent study published in the international journal European Journal of Nutrition, scientists from the University of South Australia and the University of Queensland have completed a highly successful new formulation of fish oil
    human
    clinical trials, showing that even a low-fat diet, individuals can easily absorb fish oil ingredients and benefit from them.

    , the researchers developed a self-emulsifying drug system - AquaCelle Omega-3 EE, and in a random double-blind trial, the researchers found that when taking AquaCelle products After that, patients increased their absorption of fish oil by six times, and the researchers recruited 60 participants to conduct a single 680 mg capsule, which contained EPA and DHA ethyl (omega 3s) and contained or without AquaCelle. The researchers found that when ingested capsules containing emulsifiers, the absorption and plasma concentration of fish oil and plasma in the AquaCelle group increased significantly.


    Eur J Cancer Prev: Supplementing fish oil or preventing cancer

    doi: 10.1097/CEJ.00000000045

    increase the intake of fish oil in the diet, as well as "healthy" omega-3 fatty acids in fish oil, are thought to reduce the risk of colorectal cancer. How it works is not clear, but it is thought to modify lipid signaling molecules associated with inflammation and cancer. In this article, the researchers conducted a randomized, double-blind, controlled trial of fish oil and olive oil supplements on participants with a history of colorectal adenoma.

    researchers assessed the levels of the urine and rectal lipid signaling molecules. Supplementing fish oil reduces urine PGE-M. Overall, it did not reduce rectal PGE2, but it did reduce PGE2 in participants who did not use aspirin or other nonsteroidal anti-inflammatory drugs. The genetic variation that affects cellular fatty acid levels did not change the effect of fish oil on PGE2.


    BMJ: Women's pregnancy to add fish oil or make offspring stronger

    doi: 10.1136/bmj.k3312

    , a recent study published in the international journal BMJ, from Denmark and the UK Through large randomized controlled trials, the researchers found that women's supplements with fish oil in late pregnancy or their offspring's higher body mass index by age 6 were directly related, i.e. their body's overall lean lean weight and bone mass increased by the age of 6, but the body's fat content did not increase. Animal studies have shown that adding fish oil to a pregnant diet affects the formation of body fat, but trials conducted in humans have shown that women who consume high levels of fish oil give birth to babies with high birth weight, but the effects on later prowess are not clear to researchers. So in this study, the researchers analyzed the effects of fish oil supplementation during pregnancy on the growth and body composition of future generations.

    , the researchers studied 736 pregnant women from a prospective study of
    asthma
    in Children in Copenhagen, who randomly divided them into n-3 long chain polyunsaturated fatty acids (LCPUFAs, fish oil groups) and olive oil (control group), and asked pregnant women to consume L from 24 weeks of pregnancy. CPUFAs or olive oil, which stopped until one week after birth, followed by researchers measuring the baby's BMI 11 times from birth to age 6, including height, weight, head and waist size, and timely adjustments to the baby's age and gender, showed that the infant's BMI continued to grow between the ages of 1 and 6.
    photo source:

    . medicalxpress.com. 6
    Cell Death and Different: Fish oil or

    doi, which can help repair brain and retinal damage: 10.1038/cdd.2017.55

    A team led by Dr. Nicolas Bazan of Louisiana State University's Center for Health Sciences has found for the first time that NDP1, a signaling molecule from DHA, promotes the production of a protective protein against toxic free radicals to protect the brain and retina. The study was conducted in ischemic
    stroke
    experimental models and human retinal pigment epithelial (RPE) cells, published in Cell Death and Viss.

    neuroprotector D1 (NPD1) is a lipid signaling molecule that is converted by omega-3 fatty acid 22 carbon 6 oleic acid (DHA) when cell survival is inhibited. NPD1 was discovered in 2004 by Dr Bazan and his colleagues. Oxidative stress caused by the production of damaged free radicals is the basis of cell death. Cell death can be accelerated by catastrophic events such as ischemic
    stroke
    , neurodegeneration, and blindness. The team found that injecting NPD1 into the system two hours after an experimental
    stroke
    increased the production of cycloprotein 146, known as the Goddess of Youth (Iduna). Iduna promotes DNA repair and protects cells from procedural cell death sabotally after stroke. Their findings also include NPD1 that promotes the production of Iduna and protects two RPE cells (ARPE-19 and progeny RPE cells) in oxidative stress. The researchers found that the increase in NPD1-to-Iduna activity peaked six hours after oxidative stress. The dose dependence curve showed that the activity of Iduna in both cells began to increase at a concentration of 25 nM in NPD1. These results show that NPD1 can selectively induce iduna's activity, while oxidative stress promotes the formation of NPD1, which in turn increases Iduna's activity.


    JCI Insight NEJM: Two heavyweight articles confirm that fish oil can be effective in treating asthma

    doi: 10.1056/NEJMoa1503734

    , a recent study published in the international journal JCI Insight, scientists from the University of Rochester Medical Center found that fish oil can be effective in treating asthma. Researcher Richard P. Phipps said the omega-3 fatty acids contained in fish oil reduce the production of IgE in the body, a special antibody that induces allergic reactions and asthma symptoms in people with mild asthma. But in patients with severe
    asthma
    of oral low-dose steroid drugs, omega-3 fatty acids do not work because corticosteroids in the drug can block the beneficial effects of omega-3 fatty acids.

    previous lying by researchers have found that fish oil contains specific fatty acids can regulate the function of the body's immune B cells,
    asthma
    in the body of patients to slow down and increase inflammation of the molecules tend to show an imbalance, the use of steroid drugs as a therapy can control inflammation, alleviate the symptoms of patients, but it can not effectively treat the disease. In the article, the researchers collected blood from 17 patients, isolated B cells in the lab, and studied the effects of pure omega-3 derivatives on IgE and other disease-inducing molecules, and then compared the results of 17 patients with healthy controls.


    Physiol Rep: Deep-sea fish oil can prevent cardiovascular disease

    doi: 10.14814/phy2.12438

    cardiovascular disease is the leading cause of morbidity and mortality worldwide. The incidence of cardiovascular disease increases dramatically with age, and more than half of all patients with cardiovascular disease are over 60 years of age. Recently, researchers from Penn State University School of Medicine found that 12 weeks after taking omega-3 fish oil every day, the cardiovascular health of older adults improved. The findings were published in the journal Reports of The Same.

    the incidence of cardiovascular disease increases with age because arterial blood vessels become stronger. Stiff arterial blood vessels affect blood flow and the strength of the heart's pumped blood. The most common indicators for measuring arterial vascular stiffness are pulse wave conduction speed (PWV) and enhancement index. When the heart injects blood into the blood vessels, the pressure increases, which can cause the blood vessels to protrude and form a pulse wave. PWV is the speed at which pulse waves are transmitted from one position to the next along the wall of the tube. When the pressure pulse hits the fork of the artery, a portion of the pressure pulse bounces back to the heart and shoots out of the heart along with the new pulse. Blood flow that bounces back into the heart can increase the intensity of the new pulse, which increases the amount of the amount known as the enhanced index. High PWV and high enhancement index can reflect the stiffness of arterial blood vessels.


    : Deep-sea fish oil Omega-3 New Features: Excitement

    News Reading
    :
    Omega-3 help depression by certain projects of

    published in the journal Molecular Psychiatry, found that omega-3 fatty acid EPA (20 carbon pentaicacid) has an emotional effect on patients with severe

    depression (MDD) with high levels of inflammation.

    researchers say that severe
    the diversity of symptoms and progressions
    depression makes it difficult to develop drugs to target the treatment of the disease, and that the discovery of specific biomarkers in patients with MDD is important for understanding the pathological occurrence of the disease and developing personalized treatment. In an eight-week randomized trial, 155
    diagnosed with severe
    .
    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.
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