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Multiple sclerosis (MS) describes the lesions around the pontine.
Theoretically, due to abundant vascularization, this area is less prone to vascular risk factor (VRF)-related small vessel disease (SVD)
.
On the contrary, the central bridge is supplied by the penetrating small arteries, which is prone to ischemia, hypoxia and demyelination, which is the basis for the high signal of T2 magnetic resonance imaging (MRI) in patients with VRF-SVD
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