My scientist reveals the molecular mechanism of ketamine's rapid antidepressant

On the evening of July 28, the journal Nature published an online research paper titled "Structural Basis of Ketamine Acting on Human NMDA Receptors"

Depression is one of the most common mental illnesses

"Depression is not a mental illness.

Zhu Shujia, born in 1984, has been engaged in NMDA receptor research for more than ten years.

"This meticulous and interesting study solves an important and timely problem in the structural biology of NMDA receptors

Academician Zhang Mingjie, a structural biologist, believes that this breakthrough work has extremely important scientific significance and clinical value, and is expected to lead to a better clinical performance of the drug combination for the treatment of depression

The research was completed by the Zhu Shujia research group of the Chinese Academy of Sciences Brain Science and Intelligent Technology Excellence Innovation Center (Institute of Neuroscience), the State Key Laboratory of Neuroscience, the Shanghai Brain Science and Brain-like Research Center, and the Luo Cheng research group of the Shanghai Institute of Materia Medica, Chinese Academy of Sciences