Nano-knife technology can accurately kill tumor cells.

While killing tumor cells, how do you maximize the protection of surrounding tissue from damage? Recently, at the International Symposium on Nanoknife Technology held at the General Hospital of the Chinese People's Liberation Army (301 Hospital), Professor Chen Yongliang, deputy director of hepatobiliary surgery at the hospital, and a new technology for the treatment of nano-knife tumors demonstrated by the team at the University of Louisville in Kentucky, USA, made these realitys.
tumor cell membranes are perforated under high-pressure current, resulting in tumor cell death tumor ablation is a major advance in tumor treatment in the 21st century, which allows many patients who can not be surgically removed or are not tolerant of surgical excision, can be effectively treated.
at present, commonly used technologies include radio frequency, microwave ablation (thermal melting) and liquid nitrogen ablation (cold ablation) and so on.
although they have advantages, but relying on the hot and cold effect of the problem is that killing tumor cells at the same time, it is often difficult to avoid damage to surrounding tissue. the principle of
nano-knife is to allow the cell membrane of tumor cells to undergo nano-level perforation under high-pressure current, which can lead to tumor cell death.
under the guidance of CT to carry out nano-ablation treatment 301 hospital radiation department deputy director Xiao Yueyong introduced, unlike traditional ablation technology, nano-knife is not the use of "hot" or "cold" effect for physical ablation, but through high-pressure pulse current directly destroy the cell membrane of tumor cells, not only to make tumor cells die, but also to protect the surrounding blood vessels, bile ducts, pancreatic tube and other important tissues are not affected.
at the same time, with small trauma, pain is light, quick recovery characteristics.
, nano-knife technology was first approved by the European Union in March 2010, approved by the U.S. FDA in October 2011 for clinical treatment, and officially introduced Chinese mainland at the end of June last year.
has been conducted in more than 100 central oncology hospitals around the world, treating more than 6,000 surgical patients, and its safety and efficacy have been recognized worldwide.
a study by the University of Louisville in Kentucky, usa, with data from six surgical centers in the United States, nano-knife technology can double the median survival compared to controlled patients with a history of localized progressive pancreatic cancer.
can make pancreatic, prostate and other tumors more easily to carry out surgery traditional ablation technology, mainly used in liver bile tumors, kidney tumors and other solid tumors, for the pipeline wrapped dense pancreas, never dare to act lightly, a single error may cause blood vessel rupture bile duct damage.
Chen Yongliang introduced, the advantage of nano-knife is the courage to "call the board" the most difficult "cancer king" surgery.
a pair of two steel needles, avoid the pipe accurate lying in the tumor, only a minute and a half, with 1500 to 3000 volts of high-pressure pulsed electricity, you can penetrate the tumor cells.
30 minutes, enough to make a 5cm-sized tumor cell an ant-cave collapse.
, not long ago, an 81-year-old patient with advanced stage pancreatic cancer came to 301 hospital, according to the previous conditions, the patient's tumor size and age is not suitable for surgery.
Chen Yongliang's surgical team has conducted many full discussions and decided to use nano-knife for her treatment.
team to accurately measure and locate tumor size, using a computer to automatically form the number and location of needles.
, three electrode needles are then inserted into the tumor tissue, avoiding the various pipes, each two super needles are separated by no more than 2 cm.
less than half an hour, the entire tumor cell ablation process is complete.
"apoptosis of tumor cells, which can also activate a person's immune cells to devour these necrotic tumor cells."
" Chen Yongliang said, now the patient recovered very well from surgery, the tumor basically eliminated.
in addition to pancreatic tumors, prostate, ureter and other special parts of tumor surgery can be used nano-knife technology.
with this technology, the proportion of these areas able to perform surgery can be significantly increased.
Source: Decoding Medicine.