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    Home > Biochemistry News > Natural Products News > Nanoparticles promote resveratrol stability and biological utilization (foodaily)

    Nanoparticles promote resveratrol stability and biological utilization (foodaily)

    • Last Update: 2021-02-07
    • Source: Internet
    • Author: User
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    Researchers in Portugal have used a nano-carrier system to protect resveratrol from photodegradation in a simpler and more economical way, while improving resveratrol's ability to pass through the intestinal barrier and promote absorption.University of Porto recently reported on two carrier systems, solid lipid nanoparticles (
    ) and nanostructure lipid carriers (
    ), which can be used well in dietary supplements and nutritional care products."SLNs
    are biodegradable and biomass compatible lipids that are certified as safe by
    and can be combined with resveratrol, which is highly oil-averse, water-soluble and will be widely used in dietary supplements in the future.

    in addition, the preparation of lipid nanoparticles is very simple, fast and economical,"
    ”Resveratrol resveratrol is a polyphenol widely found in grapes and wines with very good biological activity,
    2003, Harvard
    David Sinclair
    and his team first discovered that resveratrol can extend the life of yeast cells. The study, published
    Ofure, was quickly reprinted in the world's media and sparked a frenzy over anti-aging pills.based on research by the
    team, resveratrol activates the deacetylase
    gene (
    Sirt 1
    , transcriptions of
    Sirt 2
    ) in yeast, and activation of this gene has also been found in various energy-restricting animal models, including monkey models.other studies have found that resveratrol has anti-cancer, anti-inflammatory, cardiovascular health, anti-diabetes, increased energy tolerance, and the prevention of Alzheimer's disease.carrier systemUniversity of Porto found that oral resveratrol had some difficulty. Resveratrol is less water-soluble, rapidly hydrolysed after entering the body, and is quickly metabolized. In addition, trans resveratrol is a biological isomer that is sensitive to light and quickly transforms into a smooth structure (less biologically active).previous studies have used a variety of methods to try to maintain the stability of resveratrol and promote absorption. A new report describes two potentially effective nanosystructures that can be used in dietary supplements and functional foods and beverages.SLNs
    is an alternative to water-soluble solid lipid xenonyl palmate,
    to select solid lipid hexaane palmate and liquid lipid
    . Resveratrol has a encase rate of
    suggests that both carrier systems can be used for oral resveratrol.
    researchers said.the nanosysms can also reduce the photosensitivity of resveratrol, the researchers added.experiments with gastrointestinal environment simulations,
    increased the intestinal wall pass rate of resveratrol, while
    did not affect resveratrol absorption.based on the results, the researchers recommend that people use the product at meal time. When eating, the intestinal fluid secretes and increases resveratrol's ability to pass through the intestines. "SLNs
    have been shown to protect the structural stability and intestinal ability of trans resveratrol. These two lipid nanoparticles are able to maintain good compatibility with resveratrol after oral use, thus improving the efficiency of resveratrol utilization in the body.
    This article is an English version of an article which is originally in the Chinese language on and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

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