Nat Commun: Uncovering the Molecular Mysteries of The Body's T-Cell Immunity in the Elderly

, June 10, 2020 /
BiovalleyBIOON/ -- In a recent study published in the international journal
nature communications, scientists from Monash University and other institutions have gained a deeper understanding of the molecular pathways that control T-cell function and survival, as well as how they are linked to decreased Immunity to T-cells in the body of the elderlyPicture Source: Felix Kraus-Monash BDI
The researchers say the increase in T-cell metabolism observed in older adults may indicate that these T-cells are "working hard" to survive, which may contradict previous research, and that increased metabolic levels suggest the function of T cells, which may be important for developing targeted intervention strategies such as vaccines or immunotherapy to treat age-related immune system disordersT-cells play a key role in helping the body fight infections andtumorsimmune response, but the immune function of T cells decreases with the body's age, which increases the body's susceptibility to disease'We have now shown that accelerating cell metabolism, rather than arming cells to fight pathogens, may be related to the life span of T-cells, which need to increase their metabolism to survive in the less erasofable environment,' said professor La Gruta, aresearcherThis study is very important because the main marker of T-cell loss during immune aging may help researchers develop new strategies to effectively promote the survival of T-cells and enhance T-cell immunity in the elderlylaterresearchers will continue to delve into the development of new therapies and interventions to support cell metabolism in the body's aging process to help T-cell survival and survival; (BioValley Bioon.com)original origins:Quinn, K.M., Hussain, T., Kraus, Fet al.
The specials of the mins of CD8 plus T cell subsets in young and aged individuals are not snois of the .
Nat Commun 11, 2857 (2020) doi: 10.1038/s41467-020-16633-7