NAT IMMUNOL: Transcriptional Spectrum Analysis and Treatment Target Study of Oxidative Stress in Neuroinflammation
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Last Update: 2020-05-30
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Source: Internet
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Author: User
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Oxidative stress is a core part of congenital immune-induced neurodegenerationTo date, however, transcriptional profiles of congenital immune cells of the central nervous system (CNS) are unknown, and treatments for its neurotoxic function sit until now have not been widely usedrecently, researchers provided a map of innate immune cells of oxidative stress in neuro-inflammatory diseases and reported new discoveries of possible pathwaysTranscriptional spectrometry of the innate immune cells of the central nervous system produced byoxidative stress inidentified a core oxidative stress gene characteristic in which the clotting and glutathione pathway genes were shared between small glial cell populations and immersion macrophagesusing Tox-seq, and subsequent high-throughput screening of small glial cells and analysis of oxidative stress gene networks, the researchers found the glutathione-regulated compound Asivisin, which has an effective therapeutic effect on oxidative stress and axon damage in models of chronic and recurrent multiple sclerosisso oxidative stress transcription has identified neurotoxic in the central nervous system's congenital immune population and may make possible the discovery of selective neuroprotective strategies
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