Natno Biotechl: Deep interpretation! Scientists have succeeded in clearly mapping out the micro-ecosystem singo of the human gut!

In a recent study published in the international journal Nature Biotechnology entitled "A unified catalog of 204,938 reference sleuss from human gut microbiome", scientists from the European Laboratory of Molecular Biology and other institutions combined the genomes of all known bacteria in the human gut microbiome into a large database, which could help researchers delve into the association sins of even bacterial genes and proteins, and their impact on human health.
bacteria are found inside and outside the body, producing proteins that affect the body's digestion, health and susceptibility to disease, so common that there are more members of the human microbiome group than human cells, including bacteria, fungi and other microorganisms;
in order to obtain information about these bacteria, the researchers took another approach, collecting a single sample from the environment, such as the intestines, and then sequencing the DNA from the entire sample, and then using computer methods to reconstruct the genomes of individuals from thousands of species in a single sample, known as macrogenomics, which can be used as an alternative method for isolating and sequencing the DNA of individual species. Rob Finn, a
researcher, says that last year, three independent teams, including us, rebuilt thousands of gut microbiome genomes, and the big question is whether the results achieved by these teams are comparable and whether they can compile them into a very comprehensive list.
Researchers have compiled 200,000 genomes and 170 million protein sequences from more than 4,600 bacterial communities in the human gut, a new database (a unified collection of human gastrointestinal genomes and a unified gastrointestinal protein catalogue) that reveals the great diversity of the body's gut and paves the way for further research into the gut microbiome. The huge catalog, drawn
researchers, is a milestone in microbiome research and may provide scientists with a valuable resource to study the key role of every bacterium in the human gut ecosystem.
the study showed that more than 70 percent of the detected bacteria were successfully cultured in the lab, and their activity in the body is still unknown, and that comantemales, the largest group of these bacteria, was a surprise to see Comantemales so widely available, highlighting how little we really know about bacteria in the gut, and I hope this catalog will help bioinators and molecular biologists fill that gap in the next few years.
all the data collected in the database/catalog is available on the online resource Mgnify, which helps scientists analyze microbe genome data and compare it to current databases, and as research teams around the world release new databases, the catalog may expand to include microbiomes in other parts of the body, such as the skin or the inside of the mouth.
concluding that the catalog could be a valuable resource for microbiologists and clinical researchers in the future, but researchers may find more new bacterial species in underrepresented areas such as South America, Asia and Africa, and are not aware of differences and changes in bacterial diversity in different populations.
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