Nature Communications: Losing weight is light-controlled! Implanting micro-small wireless devices in your stomach can increase your satiety!

As people's lifestyles change, being overweight or obese has become one of the most important health burdens facing the world.
nearly 2 billion adults worldwide are overweight or obese, according to the World Health Organization.
China is not the country with the highest proportion of obese people, but because of its large population base, it has become the world's largest obese country.
recent years, the ecstic nerve has received widespread attention as a target for the treatment of obesity, and the ecstic nerve can sense information about satiety from the stomach wall to the brain.
with the application of wireless technology and genetic optics, neurostational stimulation devices are made lighter and simpler, and patients feel more safe and comfortable during the stimulation process.
a recent study published in the journal Nature Communications, researchers from Texas Agricultural University developed a medical device that may help lose weight and have simpler procedures for implanting it into patients.
despite the clinical benefits of having a wireless system, so far no device has been able to manipulate neuron activity inside any organ other than the brain for long and lasting periods of time.
researchers have developed a durable, multi-mode wireless platform that provides photogenetic stimulation of peripheral neurons in organs in a high-performance manner.
to collect RF energy from remote RF power systems, convert RF energy into light energy, and illuminate target areas in the stomach.
led is located in the middle rather than the end of the tether, allowing the tether to enter and penetrate the stomach and secure it to both contact points.
researchers found that ultra-thin straps (0.4 mm wide and 0.2 mm thick) were more than three times smaller than insulin syringe needles and tubes used for infusions in the stomach.
micro-small wireless device implantation device in order to determine the effectiveness of the photoelectectural system, the researchers explored the role of gastric fantrain nerve transmission in the eating behavior, first analyzed the light propagation of the LED, and determined the organ specificity required radio frequency power parameters.
found that fixing the LED to the stomach, as expected, significantly limits the propagation of light, unlike surface fit, which results in light scattering intensity well above the lecithin activation threshold.
further studied whether mice implanted with a gastric device had good tolerance, and the results showed that mice implanted with the device had the same food intake as mice with false surgery.
the activation of calca-gastric mesothyst nerves, which in turn inhibited appetite researchers were surprised to find that the biological mechanisms that coordinate hunger suppression are different from traditional knowledge.
stimulate non-stretching subjects that respond to chemicals in food, which can produce a feeling of satiety even when the stomach is not open.
addition, gastrointestinal signals are closely related to taste signals, and the gastroenterological mucosa Calca plus the ecstasy nerve is transmitted to the role of appetite suppression, which in turn reveals the mechanism of appetite suppression.
, by implanting a micro-small wireless device, light stimulates the end of the ecstic nerve to provide a full feeling, which can be beneficial for controlling appetite.
, with advances in wireless telemetry, the scalability and availability of photogenetics can be improved, which is important for the development of new therapeutic targets for the treatment of appetite disorders.