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Look at developmental disorders from a new perspective
DYRK1A is defective in neurodevelopmental disorders such as autism, microcephaly, and Down syndrome
"For a long time, researchers believed that the TOM complex is a rigid structure in the mitochondrial membrane, and its door is always open," Meisinger explained
DYRK1A acts on the TOM complex
The study’s first authors, Dr.
Journal Reference :
Corvin Walter, Adinarayana Marada, Tamara Suhm, Ralf Ernsberger, Vera Muders, Cansu Kücükköse, Pablo Sánchez-Martín, Zehan Hu, Abhishek Aich, Stefan Loroch, Fiorella Poveda-Huertes, Danieltes , Alexandra Schwierzok, Henrike Pommerening, Stanka Matic, Jan Brix, Albert Sickmann, Claudine Kraft, Jörn Dengjel, Sven Dennerlein, Tilman Brummer, F.