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Nature Medicine genetics have a significant impact on healthy longevity

 Last Update: 2022-09-21
 Source: Internet
 Author: User

summary

The effect of genetic variation on the overall burden of disease has not been fully assessed

main

Genome-wide association studies (GWASs) have identified thousands of variants

Past efforts in comparative risk assessment have included quantifying the impact of modifiable exposures (e.

An important indicator of the burden of disease is DALY

We propose a method to combine the genetic association results of 80 diseases from two biobank studies with DALY estimates from the 2019 GBD study 27 to outline the effects

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