Nature Neuroscience: Revealing the complexity of the gut brain

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Twelve unique ENCs were produced during binary divisions during development, followed by diversification of neuronal populations after mitosis.

Twelve unique ENCs were produced during binary divisions during development, followed by diversification of neuronal populations after mitosis.

Each Each ENC ENC are available through other transcription factor genes and gene families in the unique combination can be by other transcription factor genes and gene families in the unique combination of ( ( e.

First, the authors identified three different states of cells: endothelial progenitor cells, transient neuroblast populations, and differentiated or mature neurons.

Proliferation of progenitor cells to differentiate along a first branch or to another neuron proliferative progenitor cell differentiation along a first branch or to another neuron (ENC.

This study provides the ENS community with a much-needed comprehensive resource on the molecular mechanisms that regulate neuronal differentiation and regulation.

Many intestinal diseases with neuronal components can only be treated by symptomatic or surgical removal of the affected intestinal area, such as Hirschsprung's disease, which is characterized by a lack of neurons in the distal intestinal area.

Learn more about how ENS generates neuronal diversity during development, and successfully restores the benchmark for all types of ENS neurons, and then these neurons can be transformed into human ENS.

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Revealing the complexity of the gut's brain

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Diversification of molecularly defined myenteric neuron classes revealed by single-cell RNA sequencing in this message