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In 1950, Barbara Mclintock first discovered a transposon in corn and won the Nobel Prize for it
On July 13, 2021, Zhang Yong's research group and others published a research paper entitled "DNA transposons mediate duplications via transposition-independent and -dependent mechanisms in metazoans" online in Nature Communications
In this study, the research team first collected the genomes of 100 metazoans in the public database UCSC, and calculated and analyzed 370 Pack-TIR elements (Figure 1A)
The research team found that Pack-TIR has a positive linear correlation with the number of TIR transposons (Figure 2A).
In addition to the in-depth analysis of the mechanism, the research team also explored the functions of Pack-TIRs in combination with a large amount of transcriptome data and evolutionary genome data
The research was completed by the cooperation of Institute of Zoology, Chinese Academy of Sciences, Curie Institute of France, Peking University Cancer Hospital and other institutions
Link to the paper: https://doi.
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