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    Home > Active Ingredient News > Study of Nervous System > [Nature Sub-Journal] If middle-aged people lack sleep for a long time, will the risk of dementia increase?

    [Nature Sub-Journal] If middle-aged people lack sleep for a long time, will the risk of dementia increase?

    • Last Update: 2021-05-09
    • Source: Internet
    • Author: User
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    This article is original by Translational Medicine Network.
    Please indicate the source for reprinting.
    Author: chen Introduction: Recently, researchers at the University of Paris in France took a different approach and used 25-year follow-up data to reveal the relationship between long-term lack of sleep in middle-aged people and the risk of dementia.

    With the surge in social pressure, more and more people choose to sacrifice sleep time to study, work, etc.
    This is especially true for middle-aged people.

    They are both old and young, and they are the backbone of the whole family, and they are also a common group of chronic sleep deprivation.

    As we all know, there are many hazards of insufficient sleep, and there are many studies on the link between insufficient sleep and symptoms of dementia.

    However, in these studies, the follow-up time for observing sleep time and dementia is relatively short, or the elderly are checked only at the beginning, and the development and manifestation of dementia symptoms usually last for decades, so it is not clear before old age.
    Is your sleep time related to the incidence of dementia?
    Recently, researchers from the University of Paris in France conducted 25-year health data analysis on nearly 8,000 middle-aged people, and published a paper entitled “Association of sleep” in Nature Communications on April 20, 2021.
    duration in middle and old age with incidence of dementia".

    The study shows that as people get older, a link will be established between sleep and dementia.

    Middle-aged people with long-term sleep less than or equal to 6 hours have a 30% increased risk of dementia.

    At present, there are at least 35 million Alzheimer's patients in the world, and China accounts for about a quarter, ranking first in the world.

    More research predicts that by 2050, there will be more than 40 million people with Alzheimer's disease in my country, which seems to cause a great burden on the family and society.

    What's even more regrettable is that no effective treatment for Alzheimer's has been found so far, so we can only prevent it first.

    In this study, the researchers used data from Whitehall II, University of London, UK since 1985, to study the correlation between sleep time at the age of 50, 60 and 70 and dementia.

    Normal sleep time is defined as 7 hours per night.
    Participants need to self-report the length of sleep.
    Some people need to wear a wearable device to sleep to confirm whether the reported length of sleep is accurate.

    Middle-aged people's sleep time and analysis of sleep trajectory sample flow chart Researchers conduct follow-up clinical data collection every 4-5 years, and each collection lasts about 2 years, and the last collection was conducted in 2015-2016.

    At the same time, the researchers also obtained follow-up data by linking with the electronic health records of the British National Health Service (NHS) until March 31, 2019.

    Researchers found that 50 or 60-year-olds who sleep less than 6 hours a night have a higher risk of dementia compared with normal (7 hours) sleep time.

    The hazard ratios (HR) for dementia with insufficient sleep for 50-70 years old were 1.
    22 (95% confidence interval 1.
    01-1.
    48), 1.
    37 (1.
    10-1.
    72), and 1.
    24 (0.
    98-1.
    57).

    In addition, there are 70 cases of dementia with a 30% increase in the risk of dementia compared with people who continue to sleep normally at the age of 50-60, regardless of socio-demographic, behavioral, cardiometabolic and mental health factors.
    .

    These findings suggest that short sleep time in middle-aged people is associated with an increased risk of late-onset dementia.

    As the researchers said, although there is no panacea for preventing dementia, there is evidence that: not smoking, drinking moderately, maintaining mental and physical activity, and eating well are factors that can help our brain stay healthy as we age.

    Reference materials: Note: This article aims to introduce the progress of medical research and cannot be used as a reference for treatment options.

    If you need health guidance, please go to a regular hospital for treatment.

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