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Nature sub-journal: Key signaling pathways involved in tumor formation

 Last Update: 2022-01-24
 Source: Internet
 Author: User

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pulmonary cancer

breast cancer progression

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Cancer is associated with disruption of various cellular signaling pathways

To identify and characterize these central control mechanisms, a research team led by Charité and Goethe University systematically searched for altered genes found in lymphomas, cancers of the lymphatic system

The gene's role in cancer pathology has not been previously understood

Summarizing the study, Professor Keller said: "Our findings allow us to use SENP6 as a biomarker of therapeutic success following PARP inhibitor therapy

Journal Reference :

Markus Schick, Le Zhang, Sabine Maurer, Hans Carlo Maurer, Konstandina Isaakaidis, Lara Schneider, Upayan Patra, Kathrin Schunck, Elena Rohleder, Julia Hofstetter, Apoorva Baluapuri, Anna Katharina Scherger, Julia Slotta-Huspenina, Franziska Hettler, Julia Weber, Thomas Engleitner, Roman Maresch, Jolanta Slawska, Richard Lewis, Rouzanna Istvanffy, Stefan Habringer, Katja Steiger, Armin Baiker, Robert AJ Oostendorp, Cornelius Miething, Hans-Peter Lenhof, Florian Bassermann, Björn Chapuy, Matthias Wirth, Elmar Wolf, Roland Rad, Stefan Müller, Ulrich Keller.

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