Nature sub-published Fudan study: How long does it take to sleep each night is good for the brain?

Sleep plays a key role in cognitive processing and maintaining mental health, including memory consolidation and emotional processing

Sleep plays a key role in cognitive processing and maintaining mental health, including memory consolidation and emotional processing

Changes in sleep patterns, including difficulty falling and staying asleep, decreased quantity and quality of sleep, and decreased sleep efficiency, are important features of the aging process

To clarify whether the brain and genetic mechanisms are underlying the nonlinear link between sleep duration, cognition and mental health, experts from Fudan University's Institute of Brain-inspired Intelligence Science and Technology conducted a study using a large cohort from the UK Biobank , the results were published in the journal Nature Aging

The researchers obtained data on nearly 500,000 middle-aged and elderly people between the ages of 38 and 73, including their sleep patterns, mental health, and performance on a battery of cognitive tests

The researchers obtained data on nearly 500,000 middle-aged and elderly people between the ages of 38 and 73, including their sleep patterns, mental health, and performance on a battery of cognitive tests

The results showed that sleep duration, mental disorders and Alzheimer's disease were closely related in older adults

Imaging studies suggest that sleep duration is also significantly non-linearly associated with total brain surface area, global mean thickness, and cortical and subcortical gray matter volume

In addition, mediation analysis and structural equation modeling identified a unified model incorporating polygenic risk scores (PRS), sleep, brain structure, cognition, and mental health

In addition, mediation analysis and structural equation modeling identified a unified model incorporating polygenic risk scores (PRS), sleep, brain structure, cognition, and mental health

Taken together, the study highlights the importance of sleep duration to adults' cognition, mental health and well-being

references:

The brain structure and genetic mechanisms underlying the nonlinear association between sleep duration, cognition and mental health.

The brain structure and genetic mechanisms underlying the nonlinear association between sleep duration, cognition and mental health.
Nature Aging (2022) DOI: 10.
1038/s43587-022-00210-2 The brain structure and genetic mechanisms underlying the nonlinear association between sleep duration, cognition and mental health.
Nature Aging (2022) DOI: 10.
1038/s43587-022-00210-2

Leave a comment here