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Nature: What neural circuits induce hibernation?

 Last Update: 2020-06-16
 Source: Internet
 Author: User

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Hibernating mammals actively lower their body temperature to reduce energy consumption when faced with food shortagesThis ability to induce low metabolic states has attracted great interest among researchers, and there are potential medical benefitsHere, the researchers found that the rodent hypothalamus neural circuitry can induce a long-lasting low-temperature, low-metabolic state, similar to hibernationIn this state, although the levels of body temperature and oxygen consumption remain low, the ability to regulate metabolism is maintained, much like in hibernationIn addition, after recovery from this state, there were no obvious tissue and organ damage or abnormal behaviorTherefore, the results of this study could guide the development of methodological induction of state like hibernation, which will have potential applications in non-hibernating mammal species, including humans

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