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The best treatment for non-surgical treatment of large masses (5-7 cm) and node-negative non-small cell lung cancer ( NSCLC ) is not clear
The best treatment for non-surgical treatment of large masses (5-7 cm) and node-negative non-small cell lung cancer ( NSCLC ) is not clear
The study evaluated patients who received radiotherapy for non-metastatic non-small cell lung cancer (NSCLC) with tumors of 5-7 cm and negative lymph nodes registered in the National Cancer Database between 2004 and 2016
The study evaluated patients who received radiotherapy for non-metastatic non-small cell lung cancer (NSCLC) with tumors of 5-7 cm and negative lymph nodes registered in the National Cancer Database between 2004 and 2016
The study included 2020 patients, the median follow-up time was 18.
In univariate analysis, younger (<70 years), male, private insurance, treatment in non-academic centers, and larger tumors (≥6.
In the log-rank analysis, compared with patients who did not receive chemotherapy, patients who received sequential or concurrent chemotherapy had a longer survival (P<0.
OS comparison of different treatment combinations
Multivariate analysis found that there was no significant difference in survival between patients who received treatment following the NCCN guidelines and those who did not follow the NCCN guidelines (HR=1.
Multivariate analysis found that there was no significant difference in survival between patients who received treatment following the NCCN guidelines and those who did not follow the NCCN guidelines (HR=1.
Analysis of death-related factors
In summary, the study shows that young patients treated in non-academic centers are more likely to accept treatment that does not follow NCCN guidelines, and there is no significant difference in prognosis from patients who receive treatment that follows NCCN guidelines
In summary, the study shows that young patients treated in non-academic centers are more likely to accept treatment that does not follow NCCN guidelines, and there is no significant difference in prognosis from patients who receive treatment that follows NCCN guidelines
Original source:
Craig S.
Craig S.
Schneider, Robert A.
Oster, Aparna Hegde, MBBS, et al.
Nonoperative Treatment of Large (5-7 cm), Node-Negative Non--Small Cell Lung Cancer Commonly Deviates From NCCN Guidelines.
J Natl Compr Canc Netw, doi: 10.
6004/jnccn.
2021.
7043.
Published online August 12, 2021
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