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NEJM: 177Lu-PSMA-617 targeted radiotherapy for the treatment of metastatic castration-resistant prostate cancer

 Last Update: 2021-09-29
 Source: Internet
 Author: User

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Castration-resistant prostate cancer (CRPC) patients still progress after the initial continuous androgen deprivation treatment.

Recently, researchers evaluated the therapeutic effect of 177Lu-PSMA-617 on mCRPC patients

This study is an international, public, phase III trial.

immunity

A total of 831 patients participated in the study, and the baseline characteristics of the patients were similar

Compared with standard care, in the 177Lu-PSMA-617 group, imaging-based progression-free survival (median progression-free survival: 8.

Differences in progression-free survival and overall survival between groups

For patients with advanced PSMA-positive metastatic castration-resistant prostate cancer, 177Lu-PSMA-617 targeted radiotherapy can significantly improve the patient's progression-free survival rate and overall survival rate

For patients with advanced PSMA-positive metastatic castration-resistant prostate cancer, 177Lu-PSMA-617 targeted radiotherapy can significantly improve the patient’s progression-free survival rate and overall survival rate.

Original source:

Oliver Sartor et al.

Lutetium-177-PSMA-617 for Metastatic Castration-Resistant Prostate Cancer.

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