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In the study, conducted by researchers at Amgen's gene decoding company (deCODE genetics) and its partners, researchers tested serum samples from 30,576 Icelanders in six tests and a four-month serological follow-up test from 1,237 patients who were confirmed to have been infected with the new coronavirus through nucleic acid testing.
trial results showed that out of 1,215 recovered patients, 1,107 patients had antibodies (91.1%) against the new coronavirus in their serum.
It's worth noting that in recovering patients with antibodies in these serums, using two pan-IgG antibody tests, the researchers found that the antibody titer of the antibody binding domain (S1-RBD), which targets the new coronavirus N protein and the target neo-coronavirus prickly protein binding domain (S1-RBD), did not decrease significantly within 4 months of confirmation of infection.
results are different from some previously published studies.
Antibody titrations targeting the new coronavirus N protein and S1-RBD protein did not decrease within four months of diagnosis (Photo source: References. 3) The researchers note in a discussion of the article that a variety of factors may have led to differences between the study and previous studies, including the specificity and sensitivity of the detection method, the type of antigen detected, and the patient group characteristics studied.
, for example, because of extensive nucleic acid testing and screening, many of Iceland's nucleic acid-positive populations are diagnosed with no symptoms and may be healthier than the patient population in other studies.
also point out that more populations still need to be studied using proven quantitative antibody testing.
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