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Although the BNT162b2 messenger RNA vaccine has a high efficacy against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), rare breakthrough infections , including infections by health care workers, have been reported
Infect
Recently, a research article was published in the top medical journal NEJM.
diagnosis
The relevance of breakthrough infection was evaluated in a case-control analysis
Among the 1,497 fully vaccinated medical staff with available RT-PCR data, 39 cases of SARS-CoV-2 breakthrough infection were recorded
Among fully vaccinated medical staff, the occurrence of SARS-CoV-2 breakthrough infection is related to the neutralizing antibody titers during the peri-infection period
Among fully vaccinated medical staff, the occurrence of SARS-CoV-2 breakthrough infection is related to the neutralizing antibody titers during the peri-infection period