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NEJM: Efpeglenatide, a long-acting GLP-1 receptor agonist, can improve cardiovascular and renal outcomes in diabetic patients

 Last Update: 2021-07-31
 Source: Internet
 Author: User

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Diabetes patientsHeart blood vessel three times the risk of incident non-diabetic patients, and renal adverse events were also high

diabetesHeart blood vessels recently researchers examined the effects of long-acting GLP-1 receptor agonist Efpeglenatide of cardiovascular and renal outcomes in patients with type II diabetes

The AMPLITUDE-O study was carried out in 344 medical centers in 28 countries.

4076 patients participated in the study, including 2,717 in the Efpeglenatide group and 1,359 in the placebo group

The incidence of MACE in the Efpeglenatide group was 7.

Differences in risk of cardiovascular and renal events between groups

Studies believe that for patients with type II diabetes who are at risk of kidney disease and cardiovascular events, once a week Efpeglenatide treatment can significantly reduce the risk of major cardiovascular events and renal events in patients

For patients with type II diabetes who are associated with kidney disease and the risk of cardiovascular events, once a week Efpeglenatide treatment can significantly reduce the risk of major cardiovascular events and renal events

Original source:

Hertzel C.

Cardiovascular and Renal Outcomes with Efpeglenatide in Type 2 Diabetes.

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