Neurology-10,000 people followed up for 10 years: late-onset epilepsy, the mortality rate is higher than that of people without epilepsy

Late onsetEpilepsy (LOE; that is, starting from 65 years of age or older) affects a large number of people around the world, and the number is increasing

Whether the mortality rate of patients with LOE will also increase, and what may be the cause of death in this population is still unknown

Pre-stroke and neurodegenerative diseases are common causes of LOE.

It is currently unknown whether any difference in mortality between people with and without LOE is simply due to differences in these vascular comorbidities, which also increase the risk of death

In this way, Emily L.

ARIC was launched in 1987-1989 among 15,792 mainly black and white men and women in 4 communities in the United States

They analyzed a total of 9,090 participants, 678 of them showed LOE during the 11.

Compared with participants who did not experience LOE, the risk of death from LOE increased, and the adjusted hazard ratio was 2.

Compared with participants without LOE, participants with LOE had a higher mortality rate due to stroke, dementia, neurological diseases, and end-stage renal disease

The main significance of this study is the discovery: Compared with people without epilepsy, people with LOE have an increased risk of death, even after adjusting for comorbidities