Neurology: Air pollution associated with event-induced stroke, post-stroke cardiovascular events, and death: a trajectory analysis of a prospective cohort

Ambient air pollution is widely associated
with stroke morbidity and mortality.
However, its effect on stroke dynamic progression trajectories is unclear
.
A study published in Neurology explored the impact of ambient air pollution on the trajectory of
progression from health to event stroke, cardiovascular disease after stroke, and subsequent death.

318,752 participants
were found from UK Biobank.
Estimate annual concentrations of air pollution [particulate matter (PM2.
5, PM brown rice, PM10 and PM2.
5 absorbance, nitrogen dioxide (NO2) and nitrogen oxides (NOx)] by land use regression.

A multi-state regression model was used to study the influence of
air pollution on stroke development stages.

This study provides the first evidence that ambient air pollution is an important correlated factor in progressive stroke and has a different effect at different
clinical stages.
A better understanding of the different effects of atmospheric pollutants on different stroke transition stages can provide valuable insights
into health management and clinical prevention goals.

Tian F, Cai M, Li H, et al.
Air Pollution Associated With Incident Stroke, Poststroke Cardiovascular Events, and Death: A Trajectory Analysis of a Prospective Cohort [published online ahead].
of print, 2022 Sep 28].
Neurology.
2022; 10.
1212/WNL.
0000000000201316.
doi:10.
1212/WNL.
0000000000201316