Neurology: Inflammation may be the target of epilepsy treatment

Inflammation is caused by a series of inflammatory mediators and accompanying anti-inflammatory molecules, usually due to trauma, ischemia, infection or immune processes

Inflammation is caused by a series of inflammatory mediators and accompanying anti-inflammatory molecules, usually due to trauma, ischemia, infection or immune processes

There is a lot of clinical and experimental evidence that inflammation isIt plays an important role in the occurrence and maintenance of epilepsy

French et al.

Natalizumab is an anti-α4 integrin monoclonal antibody used to treat multiple sclerosis

Changes in the frequency of seizures over time

Changes in the frequency of seizures over time

This is a double-blind, randomized study of Natalizumab in the treatment of drug-resistant focal epilepsy

This is a double-blind, randomized study of Natalizumab in the treatment of drug-resistant focal epilepsy

Anti-inflammatory mechanism is one of the most promising research topics in new anti-epileptic and anti-epileptic treatments

Original source

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Safety and Efficacy of Natalizumab as Adjunctive Therapy for People With Drug-Resistant Epilepsy A Phase 2 Study Neurology Nov 2021, 97 (18) e1757-e1767; DOI: 10.
1212 / WNL.
0000000000012766

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