Neurology: Swedish studies have found a significant increase in the incidence of epilepsy after intracranial infections

Endogenous epilepsy can occur in any brain disease, and the International Anti-Epilepsy Alliance emphasizes classification from the perspective of epilepsy (International League Against Epilepsy, ILAE).
based on a meta-analysis of post-brain epilepsy published between 1988 and 2016, researchers estimate that about 8 percent of people in developed countries have seizures after intracranial infections, with higher rates in resource-poor countries.
risk of epilepsy after infection varies depending on the type of infection or adult or child.
reported that between 1990-2001 and 1995-2013, 24% and 46% of post-herpes encephalitis survivors were affected by epilepsy, and 27% and 32% of survivors of cerebral abscesses were affected by epilepsy, respectively, in 1935-1981 or 1982-2016.
2% or 13% of bacterial meningitis patients in 1935-1981 had epilepsy, depending on the condition of early seizures.
acute symptomatic seizures, persistent epilepsy, ICU hospitalization, electro-encephalogram abnormalities, and neuroradiological damage are risk factors for epilepsy after encephalitis or meningitis.
Zelano of the University of Gothenburg in Sweden and others analyzed the risk factors and risk factors for epilepsy after brain infection in Swedish adults through retrospective studies.
Based on the Swedish National Patient Registration System, they included all patients over the age of 18 without a history of epilepsy between 2000 and 2010 who were hospitalized for brain infections, with three age- and gender-matched control groups for each contact (n s 12,101 contacts and 36,228 controls).
the risk factors for Kaplan-Meier seizures after different brain infections using Cox regression analysis.
follow-up patients until the end of 2017.
results showed that the epilepsy rate was 5.9% (95% CI: 5.5-6.3) in meningitis patients, 1.2% (95% CI: 1.0-1.4) in the control group, and 1.7% (95% CI: 0.7-2.2% in patients with tick borne enitis) 7) 4.1% of patients with bacterial meningitis (95% CI: 3.3-4.9), 26.0% of patients with bacterial meningitis (95% CI: 21.5-30.5) and 30.2% of patients with encephalopathy (95% CI: 27.1-33.3).
cox regression analysis, emergency hospitalization and mechanical aeration were risk factors for epilepsy.
significance of this study is that seizures are more common after multiple brain infections in adults.
type, severity, and tendency to cause seizures during the acute phase can affect the risk of seizures later in life.
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