Neurology: The global burden of ischemic stroke from 1990 to 2019: The age-standardized incidence rate (ASIR) increased most significantly in China, and the burden of ischemic stroke in women worldwide is larger, especially in the elderly

Stroke is the leading cause of disability in adults and the leading cause of death worldwide
.

According to the 2019 Global Burden of Disease (GBD) survey results, stroke was one of the leading causes of disability-adjusted life years (DALYs) for people aged 50 years and older from 1990 to 2019

Stroke disability-adjusted life years (DALYs)

According to epidemiological studies, ischemic stroke accounts for 85% of all stroke cases
.

As such, ischemic stroke has been recognized by the United Nations as a priority target for reducing the burden of NCDs

 According to epidemiological studies, ischemic stroke accounts for 85% of all stroke cases

Annual Estimated Percentage Change (EAPC) in Global Burden of Disease (GBD ) .
EAPC provides year-to-year changes in time trends rather than total percentage changes over the study period, which provides more accurate information .
Annual Estimated Percentage Change (EAPC) Social Development Index (SDI)

No comprehensive update on the descriptive epidemiology and trends of ischemic stroke has been published since the 2017 GBD, examining ischemic stroke at global, regional and national levels from a gender, age and social development index (SDI) perspective burden
.

The GBD assessed the burden of 369 human diseases and injuries in 204 countries and territories around the world in 2019

We assessed the burden of ischemic stroke by determining temporal trends in ischemic stroke based on GBD 2019 data.

Data was extracted from the GBD 2019 dataset
.

Estimated annual percentage change (EAPC) was calculated to assess trends in ischemic stroke morbidity, mortality, and disability-adjusted life years (DALYs)

• From 1990 to 2019, the global age standardization rate (ASIR) of ischemic stroke decreased, EAPC was -0.
  43 [95% Credit Interval (CI), - 0.
  54 to -0.
  32]
  .
  
• The ASIR, ASDR, and age-standardized DALY rates of ischemic stroke were significantly higher in the high-middle and moderate social development index (SDI) regions than in other SDI regions
  .
  
  Regionally, East Asia had the highest ASIR for ischemic stroke in 2019, with the largest increase in ASIR from 1990 to 2019
  
  ASIR, ASDR, and age-standardized DALY rates remained high in moderate, intermediate-to-high SDI regions
  
  Ding Q, Liu S, Yao Y, Liu H, Cai T, Han L.
  Global, Regional, and National Burden of Ischemic Stroke, 1990-2019 [published online ahead of print, 2021 Dec 15].
  Neurology.
  2021;10.
  1212/ WNL.
  0000000000013115.
  doi:10.
  1212/WNL.
  0000000000013115Leave a message here