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Neurology: Zhejiang University: Spinocerebellar ataxia, neurofilament light chain level is closely related to disease severity

 Last Update: 2021-11-13
 Source: Internet
 Author: User

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Spinocerebellar ataxia type 2 (SCA2) is one of the most common autosomal dominant inherited ataxias in the world.

They recruited participants from a medical center in China and performed genetic diagnosis of SCA2 patients

diagnosis

49 SCA2 patients, 10 SCA2 preclinical patients and 92 control groups were included

Serum NfL levels are correlated with the disease intensity of SCA2 patients, and are higher near the estimated age of onset of SCA2 preclinical patients

Serum NfL levels are correlated with the disease intensity of SCA2 patients and are higher near the estimated age of onset of SCA2 preclinical patients

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