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    Home > Biochemistry News > Biotechnology News > Neuron: previously unknown genetic program protects neurons from degeneration

    Neuron: previously unknown genetic program protects neurons from degeneration

    • Last Update: 2021-08-28
    • Source: Internet
    • Author: User
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    Picture: In the laboratory: First author Dr.


    Volker Lannert/University of Bonn

    Researchers at the University of Bonn in Germany have discovered a previously unknown genetic program in fruit flies


    The Drosophila brain is only slightly larger than the point on i, but it is composed of about 100,000 neurons


    However, there are striking similarities between these two creatures


    WNK plays a dual role

    This important discovery was made by Dr.


    However, in adult animals, WNK seems to protect existing axons


    An important balance between protection and degradation

    However, kinases may not be directly involved in these opposite processes


    These results may provide new impetus for understanding how neurodegenerative diseases occur in humans and how to treat them


    Schmucker hopes that WNK kinases may play a role in the treatment of neurodegenerative diseases—for example, by over-activating an active ingredient to increase its ability to protect neurons


    Participating institutions and funding: This research was supported by the Belgian "Flanders Research Foundation" (FWO), the French Medical Research Foundation (FRM), the European Union (as part of the ERC start-up fund), the Humboldt Foundation, and Roger · Funding from the De Sporberg Foundation and the Thompson Family Foundation Initiative


    Published: Azadeh Izadifar et al.


    DOI

    10.


    Article title

    Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed

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