New coronavirus escapes body immune system recognition mechanism revealed

, Beijing Science and Technology Daily, January 14 (Reporter Wu Changfeng) reporter 14 from Anhui Agricultural University learned that the university's chair professor Martin A. The team of F. Bachmann and Professor Chalissa found that the surface antigen protein spacing of the new coronavirus is not conducive to the recognition of the body's immune system, and thus does not allow the body to produce a good protective antibody response. The study was published in the journal Nature.
like all viruses, an important protective mechanism against the new coronavirus is the ability to produce protective antibodies against the virus. However, there is growing evidence that, unlike other viral infections, new coronavirus infections produce lower concentrations of protective antibodies for shorter durations.
the body's immune system responds best when the virus's surface antigen proteins are spaced between 5 and 10 nanometers. The Chalissa team calculated that the average surface antigen protein spacing of the new coronavirus was 25 nanometers, which led to a significant decline in the body's immune system's ability to recognize and fight the new coronavirus, which allows the virus to escape the body's immune system's identification and attack.
the results provide a theoretical basis for the design of a more efficient new coronavirus vaccine.