New Crown Pneumonia? Infection? Tumor? Interleukin 6 helps you to parse!

In late 2019 and early 2020, the new coronavirus pneumonia attracted global attentionSevere new coronary pneumonia patients due to "cytokine storms", which cause acute respiratory distress syndrome and multi-organ failure, life-threateningand thediagnosis of cytokine stormsmainly depends on the detection of increased inflammatory factors in peripheral blood, and interleukin 6 plays an important role in both primary and secondary storms, and its content in peripheral blood is increasedAnd because interleukin 6 plays an important role in the diagnosis of cytokine storms because of its convenient and fast and high accuracy in laboratory testingand clinical trials (ChiCTR200029765) have demonstrated the effectiveness and safety of the treatment of the treatment ofthe new coronal pneumoniawith the application of the interlemic 6 receptor blocker tobead monotonicaIn addition, high concentrations of interleukin 6 can inducethrombosisformation,vascularleakage and cardiomyopathy and other related functional impairment, resulting in tissue hypoxia, low blood pressure, multi-organ dysfunctionTherefore, early blocking treatment is particularly importantinterleukin 6 as a new type of infection -related markers, also plays an important role in the clinical diagnosis of infectious diseases: (1) when infection and inflammation occur, interleukin 6 is the first to be produced, and after the production of calcitonin (PCT) and C-reactive protein (CRP) rise; (2) the increase in interleukin 6 was positively correlated with the severity of the disease, and the increase reflected the severity of the disease In particular, the increase in systemic infection is more pronounced, and its elevated levels indicate that patients are at high risk of sepsis (3) PCT, interleukin 6, CRP, the sensitivity of interleukin 6 is better than the PCT and CRP, but its specificity is not as good as the PCT, joint testing can complement each other (4) interlemic 6 can be used to evaluate the severity of infection and assess the prognosis, when interleukin 6 is too high to warn of poor prognosis in patients with severe infection in recent years, the prognosis relationship between interleukin 6 and tumor has also attracted much attention from scholars, and the study found that it is related to the prognosis of many tumors, such as nasopharyngeal cancer, esophageal cancer, colon cancer , and conventional tumor markers and interlemic 6 joint detection play an important role in tumor prognosis evaluation can be seen, interleukin 6 in the new coronavirus pneumonia, infection, tumor prognosis assessment can not be ignored Source: