New crown sorority: 30% of patients with the new crown develop edile three types of neurological symptoms.

A paper published online in the Journal of the American Medical Association, JAMA Neurology, suggests that the new coronavirus can cause brain and nervous system damage to nearly half of all severe patients.
paper, neuroscientists from Tongji Medical School of Huazhong University of Science and Technology, in conjunction with a team of researchers at St. Joseph's Hospital in the United States, examined 214 patients with the new coronavirus and found that 36.4% of them developed neurological symptoms.
severe illness, 45.4% showed neurological symptoms, including acute cerebrovascular disease, consciousness disorders, and muscle damage.
studies have shown that a significant proportion of patients with new coronavirus develop neurological symptoms.
paper pointed out that most patients with neurological symptoms appear in the early stages of the disease, in six patients with severe cerebrovascular disease, 2 patients due to sudden paraplegia was sent to the emergency department, but there was no fever, cough and other typical symptoms of new coronary pneumonia.
30% of patients with three types of nervous system clinical manifestations, the data collected from January 16, 2020 to February 19, 2020, from Wuhan Huazhong University of Science and Technology Hospital 3 designated special care centers (main area, western branch, tumor center) patients, a total of 214 patients.
clinical data from the patient's electronic medical records, which were verified by two trained neurologists. the neuroclinical symptoms of the
new coronavirus are divided into three categories: clinical manifestations of the central nervous system (dizziness, headache, consciousness disorder, acute cerebrovascular disease, co-disorder, epilepsy), clinical manifestations of the peripheral nervous system (taste disorders, olfactory disorders, visual impairment, nerve pain), and clinical manifestations of skeletal muscle injury.
, the average age of 214 patients with new coronavirus was 52.7 years, of which 126 (58.9%) were non-severe patients, 88 (41.1%) were seriously ill patients and 87 (40.7%) were male patients.
214 patients, 78 (36.4%) had a clinical manifestation of the nervous system, including 53 clinical manifestations of the central nervous system (24.8%), 19 clinical manifestations of the peripheral nervous system (8.9%) and 23 cases of skeletal muscle injury (10.7%). The most common symptoms in
patients with clinical manifestations of the central nervous system were dizziness (36 cases, or 16.8%) and headache (28 cases, or 13.1%).
patients with clinical manifestations of the peripheral nervous system, the most common were taste disorders (12 cases, 5.6%) and olfactory disorders (11 cases, or 5.1%).
paper pointed out that, in addition to cerebrovascular disease and consciousness disorders, most patients with neurological symptoms appear in the early stages of the disease, in 6 patients with severe cerebrovascular disease, 2 patients due to sudden paraplegia were sent to the emergency department, but there was no fever, cough and other typical symptoms of new coronary pneumonia.
patients were subsequently found to have lung damage through CT and were diagnosed after being tested for nucleic acid, and the paper also noted that some patients were admitted to neurology after initialexclusion of new coronary pneumonia due to headache and fever, followed by nucleic acid testing.
compared with non-severe patients, patients with severe illness are older, have more basic diseases, especially hypertension, and rarely appear fever, cough and other typical symptoms. In
patients with severe illness, there were more patients with clinical manifestations of the nervous system (40 cases, accounting for 45.5%), of which 5 cases of cerebrovascular disease, 13 cases of consciousness disorders and 17 cases of skeletal muscle injury.
only 38 (30.2%) of non-severe cases had neurological symptoms.
patients with severe neurological symptoms can lead to worsening the disease The study concluded that patients with the new coronavirus usually have neurological clinical manifestations, in which patients with severe disease seis are more likely to develop neurological symptoms, including acute cerebrovascular disease, consciousness disorders, skeletal muscle injury and so on. The presence of clinical manifestations of the nervous system in
may worsen the clinical symptoms of patients with new crowns and increase the risk of death.
, the study points out that during the outbreak of the new coronavirus, clinicians should make differential diagnosis when they see a patient's nervous system performance, doubt the likelihood of severe acute respiratory syndrome caused by the new coronavirus, avoid delayed diagnosis or misdiagnosis, lose treatment and prevent further transmission.
A paper published in the journal Medical Virology in February also noted that patients in intensive care units are unable to breathe autonomously, many of whom develop neurological symptoms such as headaches, nausea and vomiting, and that half of the patients die of respiratory failure in a short period of time.
the authors of the paper also believe that the neurons that control breathing may be affected, so the patient's condition worsens.
On March 20, wang Guiqiang, director of the infectious disease department at Peking University's No. 1 Hospital, introduced the findings of the Beijing Ditan Hospital that the new coronavirus may attack the central nervous system of the human body.
Wang Guiqiang said that the case is a critical patient, the patient in the course of treatment appeared convulsions, consciousness disorders, the performance of the central nervous system.
" this gives us an important reminder that new coronaviruses can reach the nervous system.
" Wang Guiqiang said, in clinical treatment, but also provided some important references.
Ian Jones, a virologist at the University of Reading in the UK, commented: "Observations of neurological complications in patients with the new coronavirus are noteworthy, but respiratory distress symptoms should still be a major concern for the new coronavirus."
," he said, "almost half of patients have potential health problems, and there is no direct data on the presence of the virus in the nervous system."
neurological complications are best considered as a consequence of the severity of the disease, not a new problem.
" Extended Reading: How much does the new crown virus do to humans? Through the analysis of the new coronavirus and the new coronapneumonia disease by medical institutions, it is known that the virus can attack a variety of organs and systems in the human body, and some medical research has found that the new coronavirus can attack not only the human respiratory system, circulatory system, excretion system and digestive system, but also the human reproductive system and nervous system.
1, the new coronavirus infection caused by the new coronavirus infection caused by the new coronavirus infection, is the damage caused by lung tissue mainly concentrated in the pulmonary interstitial.
on the imaging lung CT, the early appearance of a number of small spots and interstitial changes, to the lung band is obvious, and then developed into double lung multiple grinding glass shadow, immersion shadow, serious cases can appear lung reality, rare chest fluid.
2, the coronavirus causes liver damage Recently, the team of researchers in the international leading journal "The Lancet Gastroenterology and Hepatology" published an article online, to explore the link between the new coronavirus pneumonia (COVID-19) and liver damage in patients.
researchers found that COVID-19-induced liver damage was closely related to congenital immune dysfunction caused by the virus.
notable, this change in immune balance occurs more with age, so older patients are expected to become worse off and more dependent on the clotting and hemolytic fiber pathways.
3, after the birth of secondary liver injury, the top medical journal "The Lancet" published on January 30, Beijing time, 99 cases of new coronary pneumonia study has been concerned about liver damage.
the paper mentioned that the first performance of patients with new coronary pneumonia is very rare, and secondary liver injury is more common.
the risk of COVID-19 is higher in patients with chronic liver disease and cirrhosis.
4, the new coronavirus will attack the kidneys in a recent paper called "Caution on Kidney Sofers of 2019-nCoV Patients" suggests that the kidneys may be one of the main targets of the new coronavirus.
the paper studied 59 cases of new coronavirus infection patients.
concluded that ACE2, a key receptor for the new coronavirus, had high levels of expression in the human kidneys, nearly 100 times higher than the lungs, and that infected people may have extensive kidney damage.
5, COVID-19 also causes heart damage, experts at the University of Texas Houston Health Science Center published in the Journal of the American Medical Association: Cardiology, said THAT COVID-19 may have fatal consequences for potential cardiovascular patients, even in patients without potential heart disease.
clinical bulletin issued by the American College of Cardiology, COVID-19 had a fatality rate of 10.5 percent for patients with cardiovascular disease.
it is expected that major cardiovascular complications associated with COVID-19 will occur in patients with severe symptoms.
infected with the new crown virus, why is it mild and severe? Foreign media: The answer may be hidden in genes According to the Buenos Aires Economic News Network in Argentina on March 28th, scientists are looking for the genome of patients with new crowns to explain why some patients show obvious symptoms, while others are mild.
: The Us weekly Science has revealed that experts around the world have launched a research project to track genetic changes in patients with new coronary pneumonia, in order to explain why some patients are mild, while others are severely ill.
the new coronavirus is a selective and strange virus, only a few infected people will show obvious symptoms.
Although the most severe groups are usually older people or people with underlying diseases such as heart disease, some of those who die from new coronary pneumonia have been healthy or even relatively young.
the researchers decided to track the patient's genome in search of genetic variants that could explain the mystery. The genomes could be used to identify people most at risk of contracting the virus and those who are less susceptible, while also helping to find new treatments, according to a new study published in the journal Science,
.
the study included patients with new coronary pneumonia in hard-hit areas such as Italy, and the researchers tried to compare the genomes of patients with mild or asymptomatic pneumonia with more severe symptoms but not underlying diseases such as diabetes, heart disease or lung disease.
researchers point out that clinical results show significant differences between countries.
researchers say it is difficult to predict the results of the genome study.
gene called Angiotensin-transforming enzyme II (ACE2) is the focus of researchers.
researchers have found that the new coronavirus is likely to use the gene to enter respiratory cells.
experts say the gene variant of ACE2 may make it easier or harder for the virus to enter cells.
In addition to ACE2, scientists want to know whether differences in human white blood cell antigen genes affect the severity of symptoms of new coronary pneumonia.
gene can affect the immune system's response to viruses and bacteria.
Health Tips: For this new virus, many things are unknown, we need more time to clinical case observation and research.
Although the cure rate of the new crown pneumonia is very high, but its physical injury and impact is not to be underestimated, we should try to avoid infection with the virus, work together to do a good job of epidemic prevention and control, strictly prevent foreign imported cases caused by a secondary outbreak.
Source: Red Star News reporter Wang Yalin intern Li Xiaozhou, The Ministry of Research, if water often laughs health.