New discoveries have been made in the mechanism by which alamide enzymes affect material communication between silky blue bacterial cells.

Biotechnology Channel News: Zhao Jindong Of Peking University School of Life Sciences recently made new progress in the mechanism of material communication between the adjacent cells of silky blue bacteria, the work found that amylaminease on the blue bacterial cell material communication (intercellular communication) and heterocytostic differentiation is necessary, revealing the important role of material communication between cells on the formation of pattern.
results were published online February 6, 2017 at PNAS.
is a special cell that differentiates nitrogen fixation in the absence of nitrogen from the fishy algae-like silky blue bacteria (Anabaena 7120), and about every 10 nutritional cells there is a heterogeneum, a format that forms one of the simplest two-dimensional formats in the biological world and has a divisive effect on the differentiation of the uterine nucleus multicellular, and Anabaena 7120 is also used as a model organism to study cell differentiation and format formation.
the differentiation of this format requires the regulation of various signal molecules, the circulation of signaling molecules in mycelium needs to rely on the material communication between cells.
electroscopic technology has found that there is a "channels"-like structure between the adjacent cells of blue bacteria, which allows direct communication between cytokines.
channels penetrate the peptide polysaccharide layer on the cell board (septa) and form nanopores in the middle of the cell plate.
team has discovered a new hydrolyzed bacterial peptide polysaccharide layer of alamidease (AmiC3) that plays an important role in material communication between blue bacterial cells.
AmiC3 is located on the cell division ring in peritonal space, the missing mutant (M40) of AmiC3 causes Anabaena 7120 not to differentiate heterogenous cells, and through fluorescence quenching recovery experiments of small fluorescent molecules, it is proved that the material communication between M40 cytonucletes is impaired, and the expression of hetR and PatS, is disturbed under the condition of nitrogen reduction induction.
photo shows that the M40's nanopores are much smaller in diameter than the wild type, indicating that AmiC3 affects the dilation of nanopores, preventing the signal molecules that induce heterogeneity from spreading through channels, leading to format differentiation disorders.
the results explain the far-reaching contradiction between the diameter results of previous electroscopes in this field and promote the study of the mechanism by which blue bacteria channels are formed.
.