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    Home > Active Ingredient News > Drugs Articles > New ink 3D prints out "bones" with live cells

    New ink 3D prints out "bones" with live cells

    • Last Update: 2021-02-10
    • Source: Internet
    • Author: User
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    Scientists at the University of New South Wales in Australia have developed a ceramic-based "ink" that allows surgeons to 3D print bones with living cells to repair damaged bone tissue, according to a new report on the daily Science website. The study was published in the recent academic journal Advanced Functional Materials.Using a special ink made of calcium phosphate, combined with a 3D printer, the researchers developed a new technique called "All-round Ceramic Cell Suspension Bioprinting" (COBICS), which can print out bone structures that harden after a few minutes of water.Dr Iman Rouhani, of the University of New South Wales School of Chemistry, said: "The composition of this ink enables nanocrystalline in a water-based environment, using a solidification mechanism to convert inorgic ink into mechanical interlocking urn nanocrystals. "The chemical structure it forms is similar to that of a bone, and when ink binds to collagen containing living cells, it can form bone-like tissue. Ink preparation and its rapid and non-toxic transformation in the organism, and only in its biological environment, such as body fluids, can provide surgeons with sufficient working time.Associate Professor Christopher Kilian, who co-developed the breakthrough technique with Dr Rouhani, said: "The cool thing about this technology is that we can squeeze ink directly into a cellular area, such as a hole in a patient's bone, so that it goes straight into a bone containing cells, blood vessels and fat, and print out bone-like structures in the region that already contain live cells." "a unique technology," he said. "While the idea of 3D-printed bone-like structures is not new, this is the first time that this material can be created at room temperature -- with live cells and without irritating chemicals or radiation," Dr. Rouhani said. The3D printing as part of a 3D printing structure, according to a new report. This technology is ideal for clinical applications of bone defect in-place repair, such as trauma, cancer or large bone tissue defects, and can also be used for disease modeling, drug screening, etc. One day, a 3D printer may become a permanent fixture in the operating room.Next, the researchers will conduct in vivo trials in animal models to see if living cells in bone-like structures continue to grow after implanting bone tissue.Editor-in-chiefis nothing new to achieve fine 3D bioprinting at a microscopic scale, but live cell printing remains a new challenge in this area. For example, printing is not accurate enough, the time window is too short, the material is not friendly enough to cells, etc. , are all questions to be considered. In the new study, the materials used to print bones have never been more closely fit and the technology has become more sophisticated, undoubtedly taking an important step towards live cell printing. (Science and Technology Daily)
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