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    Home > Food News > Food Articles > New research could increase the capacity of microbial "cell factories"

    New research could increase the capacity of microbial "cell factories"

    • Last Update: 2021-03-16
    • Source: Internet
    • Author: User
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    many microorganisms are now used to produce the drugs and chemical raw materials needed by humans, and their tiny cells are a "cell factory". An international team recently successfully analyzed the characteristics of different "production lines" in the "cell factory" to help increase the production capacity of microorganisms.
    In a paper published recently in the National
    Journal, researchers at the Danish Technical University and other institutions said they analyzed the characteristics of E. coli and yeast, two common "cell factories", and found that they had different production paths, such as different "production lines", when producing the energy molecule adenosine triphosphate.
    E. coli, for example, one "production line" consumes an average of 23.5 adenosine triphosphate per glucose molecule, while the other "production line" produces only 11. However, while the previous "production line" produced high yields, it was less efficient to use proteins from the other raw material, requiring more protein per adenosine triphosphate than the 21st "production line".
    adenosine triphosphate provides energy for cellular activity. If there were more adenosine triphosphate in microbial cells, the number of products produced by "cell factories" would increase, the researchers said.
    research shows that the best way for microbial cells to produce adenosine triphosphate is not to rely solely on a single "production line", but to get the highest total capacity by distributing the right amount of protein to different "production lines".
    the findings also suggest that in the future it is possible to genetically engineer the metabolism inside microbial cells to match their "production lines" more to production needs, allowing "cell factories" to better serve humans, the researchers said. (Source: Xinhua News Agency)
    relevant paper information:
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