New research from Nature confirms that mRNA vaccines are effective against 16 mutated new coronaviruses including Delta

Since the new coronavirus delta (Delta) variant has been circulating in many parts of the world, the so-called "breakthrough infection"-that is, the number of cases still infected with the new coronavirus after vaccination has increased

A few days ago, the top academic journal "Nature" published an important paper online in the form of "Accelerated Article Preview" to answer this question

The Yale University research team tested blood samples from vaccinators and confirmed that two existing mRNA vaccines can enhance the immune system’s response to infection and prevent more than a dozen new coronavirus variants, including the delta variant

Yale University immunologist Professor Akiko Iwasaki, epidemiologists Professor Nathan Grubaugh, and Professor Saad Omer co-led the research

▲Researchers regularly collected blood samples for evaluation from before the participants received the vaccine to 70 days after the second dose (picture source: reference [1])

Then, the researchers evaluated these blood samples using live viruses from 16 COVID-19 mutant strains that had been discovered and isolated

Although the intensity of the immune response varies from person to person and from variant strains, in general, researchers have seen in the samples provided by all volunteers that the immune response is enhanced after vaccination

The researchers also conducted a comprehensive analysis of the immune escape of various mutant viruses.

▲Key mutation sites of different variants of new coronaviruses and changes in the neutralizing activity of the vaccinator's serum against the virus (picture source: reference [1])

In this study, the scientists also compared volunteers who had been infected with the new crown before vaccination with volunteers who had not been infected

Note: The original text has been deleted

Reference materials:

[1] Carolina Lucas et al.

[2] Vaccines effective against most SARS-CoV-2 variants.