New research shows that anthocyanin can increase the function of deacetylase 6 in cancer cells

Recently, published in the Journal of scientific report, a new study from the University of eastern Finland shows that the natural pigment (Anthocyanin) in berries can increase the function of deacetylase 6 in cancer cells It is known that SIRT6, for short, is an enzyme that regulates gene expression and controls cell functions through key cell signaling pathways Aging will lead to changes in the function of this enzyme, which will lead to the development of various diseases SIRT6 is an unknown enzyme, which is also related to glucose metabolism It is said that the regulation of deacetylase 6 may open up a new way for cancer treatment The researchers found that in human colorectal cancer cells, anthocyanin increased SIRT6 enzyme level, decreased the expression of Twist1 and GLUT1 oncogenes, and increased the expression of tumor suppressor FoxO3 gene The researchers also designed a computer model that allowed them to predict how different flavonoids in plants regulate SIRT6 enzymes The results showed that anthocyanin increased SIRT6 activation, which may play a role in the pathogenesis of cancer