echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Infection > New study: Gene that makes new crown symptoms worse, can prevent HIV infection

    New study: Gene that makes new crown symptoms worse, can prevent HIV infection

    • Last Update: 2022-04-19
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

    Some people become very ill after contracting SARS-CoV-2, while others have only mild symptoms or no symptoms at all
    .


    In addition to chronic disease risk factors such as advanced age and diabetes , our genetics also contribute to this phenomenon


    Some people become very ill after contracting SARS-CoV-2, while others have only mild symptoms or no symptoms at all


    A study led by Germany's Max Planck Institute for Evolutionary Anthropology (MPI-EVA) has shown that the same genetic variant that increases the risk of severe illness from COVID-19 protects against another serious disease -- which infects a person with HIV.
    The risk of the virus was reduced by 27%


    We are born with genetic variants that can increase or decrease our risk of severe COVID-19
    .


    A major genetic risk variant of severe COVID-19, the one we inherit from Neanderthals, is surprisingly common


    We are born with genetic variants that can increase or decrease our risk of severe COVID-19


    In the fall of 2020, Hugo Zeberg of Karolinska Institutet and MPI-EVA and Svante Pääbo of MPI-EVA have discovered that we inherit a major genetic risk variant from Neanderthals that increases the risk of severe COVID-19
    .


    In the spring of 2021, they studied this variant in ancient human DNA and observed that its frequency has increased significantly since the last ice age


    In the fall of 2020, Hugo Zeberg of Karolinska Institutet and MPI-EVA and Svante Pääbo of MPI-EVA have discovered that we inherit a major genetic risk variant from Neanderthals that increases the risk of severe COVID-19


    This genetic risk variant is located on chromosome 3 in a region of many genes
    .


    In its vicinity are several genes encoding receptors in the immune system


    This genetic risk variant is located on chromosome 3 in a region of many genes


     

    However, because HIV only emerged in the 20th century, reducing the risk of developing the infectious disease cannot explain why this genetic risk variant of COVID-19 was so prevalent in humans as early as 10,000 years ago
    .


    Zeberg concluded, "Today we know that this risk variant of COVID-19 provides protection against HIV infection


    However, because HIV only emerged in the 20th century, reducing the risk of developing the infectious disease cannot explain why this genetic risk variant of COVID-19 was so prevalent in humans as early as 10,000 years ago


    Reference:
    Hugo Zeberg.
    The major genetic risk factor for severe COVID-19 is associated with protection against HIV.
    PNAS, 2022, doi:10.
    1073/pnas.
    2116435119.

    Reference:
    Hugo Zeberg.
    The major genetic risk factor for severe COVID-19 is associated with protection against HIV.
    PNAS, 2022, doi:10.
    1073/pnas.
    2116435119.
    Leave a message here
    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.