New study helps combat neuropathy

Neuropathic pain is induced by neurological damage or disorders, which has always been a problem in the medical fieldThe researchers analyzed the mechanisms of neuropathic pain, according to a press release from the Fraunhofer Institute for Molecular Biology and Applied Ecology in GermanyThe nervous system sends an "alarm" signal to the immune system in conditions such as injury, but when immune cells are induced to the injured site, they sometimes lead to long-term inflammation, which can lead to persistent neurological pain that eventually develops into chronic painin this process, prostaglandin E2 is an important signal substanceCommonly used painkillers such as ibuprofen and dichlorofenic acid are used to suppress the production of prostaglandin E2, which has an effect on pain reliefresearchers have found another way to suppress painTo function, prostaglandin E2 needs to bind to a receptor that is highly correlated with a signaling molecule called CCL2Studies have shown that pain attacks can also be significantly reduced by using antibodies to suppress the function of CCL2 signaling molecules when drugs such as ibuprofen do not workThis method is expected to be used in the early prevention and treatment of neuropathic painThe findings have been published in the American Journal of Biochemistry.