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The drug must be safe, not only for the patient; for the pregnant patient, the drug must also be safe for the fetus still in the womb
However, these cell culture tests are a highly simplified version of what happens in the uterus
Chips with different cell types
Researchers from the Department of Biosystems Science and Engineering at ETH Zurich in Basel have now devised a laboratory test that incorporates the effects of the placenta into the embryo toxicity assessment
By the way, these experiments cannot produce viable embryos
Test found indirect damage
To prove the functionality of the new test, the researchers used particles that would not harm embryos even if they directly contact them
Now, the researchers hope to further develop their system to more suitable plastic materials
The team’s goal is to create a new test method that is also easy to use in the pharmaceutical industry
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