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Dr. Duan introduced NMN around four aspects: Talking about the rationale, why is this kind of substance important? When it to intervention, is this substance really effective? How much support does effectiveness have when it talks about the level of evidence? Talk about heat, scientific research into the market, but also need the world and what is NMN? NMN, also known as niacin mononucleotides, is a substance inherent in the body, and some fruits and vegetables also contain NMN.
in the human body, NMN is one of the prelude substances of NAD plus, NMN functions, the core is achieved by converting to NAD plus this substance.
so NAD plus is the real big boss behind it.
about aging, in fact, old is not a problem, decay is the key.
as we age, what is the underlying path of this decline?The latest compilation of aging biology studies in 2019 summarizes two core issues in decades of aging research, the second of which mentions that as we age, the decline in in-cell NAD-plus levels may be one of the factors for aging.
mention of NAD plus in such a highly general academic summary, which shows the importance of NAD plus in the aging process.
NAD plus involves a wide range of in-cell reactions, including energy metabolism (energy activity, energy production), chromosome stability, DNA repair, and activation of the longevity protein sirtuins, and NAD plus is a consumable substance, most of which need to be consumed to maintain normal functioning.
, especially the activation of longevity protein families, including sirtuins 1 to 7, is the core longevity mechanism.
, NAD plus is very important.
study also showed that as we age, the synthesis of NAD plus decreases gradually and consumption increases gradually, so the total amount of NAD plus decreases.
this reduction is also highly associated with aging and disease.
intervention is preceded by a rational inference.
so that by active intervention, that is, supplementing NAD plus to verify whether NAD plus really plays an important role in the aging process? Results A large number of animal experiments showed that by raising the level of NAD-plus, it was true that the quality of health was improved in many directions and the symptoms of aging were delayed.
can be seen from the map, involving a wide range of areas, including the nervous system, liver and kidneys, vascular muscle health improvements and so on.
addition, ways to supplement NAD plus include exercise and dietary restrictions, as well as NAD plus supplements.
level of evidence Science is talking about evidence, talking about repeatable verification.
evidence-based medicine, as we often say, is to value the level of evidence.
NAD-plus-related research, which accounts for 20 percent of all aging-related literature since 2019, is a high percentage, with many top-level journals like CNS, and new evidence is emerging, involving hundreds of scientists from dozens of prestigious universities around the world.
overall, this level of evidence is rare.
Before I read the Ph.D. period there was a paragraph, students on their own paper can be published in the heart of the bottomless, the tutor one by one put the final conclusions are added to the possibility, I do not say it must be so, but it may be so, it seems impeccable, the paper was successfully published.
that a small amount of scientific research is actually difficult to determine, but if the number of scientific research is very large, it can turn the possible into a probable.
it might be useful to go from NAD plus to NAD plus.
heat NMN as one of the substances that can supplement NAD-plus, from scientific research to the market, can become the "not old god medicine", not to go without the propaganda of scientists and the hot speculation of the mainstream media.
representative figures include Professor David Sinclair of Harvard Medical School, who says he takes them every day, feels much younger, and the whole family is eating, and it works well.
You look at the media headlines are very eye-catching, some magazines likened NAD plus to the fountain of youth, some magazines say NAD plus is the closest thing to a long-lived medicine, and say that the future can be a cup of coffee a day price, easily live to 150 years old.
NMN itself is a natural substance, theoretically safer, the efficacy is so attractive, so several businesses began to launch products, consumers are also actively trying.
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