npj Parkinsons Dis: Gait speed, which can reflect the living state of Parkinson's patients

Movement disorders in Parkinson's disease (PD) are often characterized by tremors, postural instability, and decreased gait speed

Movement disorders in Parkinson's disease (PD) are often characterized by tremors, postural instability, and decreased gait speed

Figure 1 Title map of the paper

Figure 1 Title map of the paper

Therefore, treatment of Parkinson's disease focuses on the use of dopamine compensation (primarily levodopa) and surgical approaches (such as deep brain stimulation) to control motor and non-motor symptoms

Therefore, treatment of Parkinson's disease focuses on the use of dopamine compensation (primarily levodopa) and surgical approaches (such as deep brain stimulation) to control motor and non-motor symptoms

Based on IMU signals or derived gait parameters, one can classify early PD, study subtle differences between PD patients, predict freezing of gait, monitor PD symptoms, and levodopa responses during long-term daily activities

Among various gait parameters, gait speed is often considered the sixth vital sign and has been shown to be a reliable measure in diagnosis and a marker of functional decline

Being wearable, the IMU allows assessment of gait in both clinical and home settings

For example, studies have shown that during daily activities, gait speed in PD patients can be reduced by 30% compared to the clinic

Furthermore, the environment at home or outdoors is different, where there are multiple obstacles and is more complex compared to the clinical environment

They found that, on average, patients had similar patterns in the clinic and in their daily activities

In addition, the number of doses taken throughout the day was somewhat correlated with differences between clinics and households

In addition, the number of doses taken throughout the day was somewhat correlated with differences between clinics and households

Overall, only about 3 percent had a gait speed equal to or greater than the patient's ability in the clinic

Gait measurement can better assist in the control of drug intake in PD because it takes into account both functional capacity and continuous monitoring of gait speed under real-life conditions

Original source:
Atrsaei A, Corrà MF, Dadashi F, et al.
Gait speed in clinical and daily living assessments in Parkinson's disease patients: performance versus capacity.
npj Parkinsons Dis.
2021;7(1):24.
doi:10.
1038/s41531 -021-00171-0 Gait speed in clinical and daily living assessments in Parkinson's disease patients: performance versus capacity.


Leave a comment here