-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
- Cosmetic Ingredient
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
Yimaitong compiles and organizes, please do not reprint without authorization.
Introduction: Studies have shown that to reduce the risk of type 2 diabetes in patients with polycystic ovary syndrome, weight loss is the key! Patients with polycystic ovary syndrome (PCOS) are more likely to develop type 2 diabetes (T2DM), which has been confirmed by many studies.
However, for disease prevention, it is obviously very important to explore the real reason behind it.
The latest research results published in 2021ENDO show that obesity plays a major mediating role in the high risk of T2DM in such patients, and it is also a target for preventing or reversing this comorbidity.
In short, to reduce the risk of T2DM in PCOS patients, we should focus on losing weight.
An inescapable topic-PCOS and obesity Most women with PCOS are obese, and it is well known that obesity is a known risk factor for T2DM, so the high incidence of diabetes in such patients seems to be easy to understand.
However, considering that PCOS itself is associated with abnormal carbohydrate metabolism, it may also have a direct impact on the risk of T2DM.
So, is the increase in T2DM risk due to PCOS itself or obesity? Need to explore.
This study included 12 related studies, including 224284 female participants, of which 45361 had PCOS and 5717 had T2DM.
All included studies involved obesity (BMI>30kg/m^2) or non-obese stratified analysis data.
Among PCOS patients, obesity increases the risk of diabetes by three times.
➤Comparing without considering BMI, overall, the relative risk of T2DM in PCOS patients is more than three times that of non-PCOS patients (RR 3.
13; P<0.
001).➤Among non-obese women, the T2DM risk of PCOS patients is numerically higher than that of non-PCOS people (RR, 2.
68), but the confidence interval is larger (95%CI: 0.
97-7.
49).
➤In women with PCOS, the risk of T2DM in obese people was more than four times that of non-obese people and the risk increased significantly (RR 4.
20; P<0.
001).
Clinical Implications This study shows that obesity is the main and changeable risk factor for diabetes in women with PCOS.
In order to reduce the risk of diabetes with PCOS in the future, clinical weight should be actively managed.
Introduction: Studies have shown that to reduce the risk of type 2 diabetes in patients with polycystic ovary syndrome, weight loss is the key! Patients with polycystic ovary syndrome (PCOS) are more likely to develop type 2 diabetes (T2DM), which has been confirmed by many studies.
However, for disease prevention, it is obviously very important to explore the real reason behind it.
The latest research results published in 2021ENDO show that obesity plays a major mediating role in the high risk of T2DM in such patients, and it is also a target for preventing or reversing this comorbidity.
In short, to reduce the risk of T2DM in PCOS patients, we should focus on losing weight.
An inescapable topic-PCOS and obesity Most women with PCOS are obese, and it is well known that obesity is a known risk factor for T2DM, so the high incidence of diabetes in such patients seems to be easy to understand.
However, considering that PCOS itself is associated with abnormal carbohydrate metabolism, it may also have a direct impact on the risk of T2DM.
So, is the increase in T2DM risk due to PCOS itself or obesity? Need to explore.
This study included 12 related studies, including 224284 female participants, of which 45361 had PCOS and 5717 had T2DM.
All included studies involved obesity (BMI>30kg/m^2) or non-obese stratified analysis data.
Among PCOS patients, obesity increases the risk of diabetes by three times.
➤Comparing without considering BMI, overall, the relative risk of T2DM in PCOS patients is more than three times that of non-PCOS patients (RR 3.
13; P<0.
001).➤Among non-obese women, the T2DM risk of PCOS patients is numerically higher than that of non-PCOS people (RR, 2.
68), but the confidence interval is larger (95%CI: 0.
97-7.
49).
➤In women with PCOS, the risk of T2DM in obese people was more than four times that of non-obese people and the risk increased significantly (RR 4.
20; P<0.
001).
Clinical Implications This study shows that obesity is the main and changeable risk factor for diabetes in women with PCOS.
In order to reduce the risk of diabetes with PCOS in the future, clinical weight should be actively managed.
