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    Home > Food News > Nutrition News > Obesity significantly increases heart failure risk in postmenopausal women

    Obesity significantly increases heart failure risk in postmenopausal women

    • Last Update: 2022-05-28
    • Source: Internet
    • Author: User
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    Women entering menopause before age 45 are known to have a higher risk of heart failure, and women who are obese have a significantly increased risk of heart failure going through postmenopause -- age 55 or older, according to the latest study published in the Journal of the American Heart Association, An open access, peer-reviewed journal of the American Heart Association
    .

    According to the American Heart Association, women produce less estrogen and progesterone after menopause, a change that increases the risk of cardiovascular disease, including heart failure
    .
    Menopause usually occurs between the ages of 45 and 55, however, according to some studies, the average age of natural menopause has increased by 1.
    5 years over the past 60 years

    .
    In the 1959-2018 National Health and Nutrition Examination Survey (NHANES), the prevalence of premature menopause (before age 45) was 12.
    6% and the prevalence of late menopause (after age 55) was 14.
    2%

    .

    Previous research has found that women who go through menopause earlier have a higher risk of heart failure
    .
    Heart failure is diagnosed when the heart cannot pump enough blood and oxygen to keep the body's organs working properly

    .

    "The knowledge gap may influence the incidence of postmenopausal-onset heart failure in people aged 55 or older," according to lead study author, IMO Ebong, MD, MS, associate professor of medicine in the Division of Cardiovascular Medicine at the University of California, Davis in Sacramento, California
    .

    "We know that obesity increases the risk of heart failure, and the onset of menopause is associated with increased physical obesity," Ebong said
    .
    "In our study, we investigated whether and how obesity affects the relationship between age at menopause and future risk of heart failure

    .
    "

    Researchers analyzed health data from nearly 4,500 postmenopausal women who participated in the Atherosclerosis Risk in Community (ARIC) study
    .
    ARIC is a long-term research program that began recruiting participants in 1987 and focused on measuring the association between known and suspected heart disease risk factors and the development of heart disease in adults in four different communities in the United States: Full Sail, North Carolina Austin County; Jackson, Mississippi; suburban Minneapolis; and Washington County, Maryland

    .
    Six follow-up visits were completed through 2019

    .

    For analysis, participants were grouped by age at entering menopause: less than 45 years; 45-49 years; 50 years; 55 years and older
    .
    At the fourth visit, the mean age of study participants was 63.
    5 years

    .
    Women diagnosed with heart failure prior to the fourth study visit were excluded from analysis in this study

    .

    The women provided their age at menopause and had their weight measured at the fourth follow-up visit for many of the baseline measurements and assessments
    .
    They were then classified by weight into three groups: normal weight (if body mass index (BMI) was between 18.
    5 - 24.
    9 kg/m2); overweight (if BMI was between 25.
    0 - 29.
    9 kg/m2); obese ( BMI of 30 kg/m² or more)

    .
    In addition, abdominal obesity can also be found if the waist circumference at the navel is 35 inches or more

    .

    After adjusting for a variety of other health and life>
    .
    During an average follow-up of 16.
    5 years, about 900 women developed heart failure, which resulted in hospitalization or death

    .

    The analysis found significant links between age at menopause, BMI and waist circumference and heart failure risk:

    • For every 6-point increase in BMI, the risk of heart failure increased by 39% for women who were premenopausal before age 45; 33% for the 45-49 age group; and for women who were postmenopausal (over 55) double (2.
      02 times)

      .
      Among menopausal women aged 50-54, higher BMI was not associated with an increased risk of heart failure

      .

    • For women 55 or older entering menopause, each 6-inch increase in waist circumference nearly tripled (2.
      93 times higher) the risk of heart failure

      .

    • Waist circumference did not significantly increase the risk of heart failure in any other women of menopausal age
      .

    "We had expected that the effect of obesity on heart failure risk would be most pronounced in women who had gone through menopause earlier
    .
    This was not the case

    .
    " "The deleterious effect of obesity on heart failure risk was most pronounced in women who were later in menopause

    .
    "

    Ebong said the information provided by this study may be useful in screening for heart failure and counseling postmenopausal women on heart failure prevention
    .

    "The age at which women enter menopause is an important factor, and women should share this information with their doctors to guide the assessment of their risk of heart failure," Ebong said
    .
    "Women in early menopause should be informed of their increased risk and advised to adopt healthy life>
    .
    Women in late menopause should be specifically advised to maintain a healthy weight and prevent obesity to reduce their risk of developing heart failure in the future

    .
    "

    The current study is limited because it did not include enough women to analyze the different types of heart failure individually
    .

    "Our analysis should be repeated according to heart failure subtype to preserve and reduce ejection fraction heart failure to gain a clearer picture of heart failure risk estimates and to guide screening and prevention protocols," Ebong said
    .

    AHA.
    121.
    024461

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