Omega-3 fatty acids can be used in colon cancer treatment

a review published by Dupertuis of the University of GenevaHospital, who argues that omega-3 unsaturated fatty acids can be used not only for cancer prevention, but also in colon cancer treatment(Curr Opin Clin Nutr Metab Care 2007, 10:427)cell culture and animal experiments have shown that omega-3 fatty acids can increase cytotoxicity of some anticancer drugsIn several colon cancer cell systems, omega-3 fatty acids combined with 5-fluorourea can increase its growth inhibitionIn addition, recent studies have shown that EPA and DHA can increase the sensitivity oftumorto radiation therapy and reduce mucosal and epithelial damage caused by radiation therapyThe researchers speculate that the mechanism may be related to lipid peroxidation, as the anti-cancer effects of omega-3 fatty acids can be destroyed by vitamin EInvivia trials have also confirmed that omega-3 fatty acids have a more significant cancer-suppressing advantage than omega-6 fatty acidsThe synthesis of the EPA can be reduced by the synthesis of thetumor
angiogenesis, inflammation, andmetastasis oftumorDupertuis et al believe that omega-3 fatty acids can be synergistic with chemotherapy or radiotherapy to kill tumor cells by increasing oxidative stress In this process, omega-3 fatty acids can reduce tumor angiogenesis, reduce inflammation, and avoid tumor metastasis