Omega-3 fatty acids have been shown to relieve early and late allergic conjunctivitis

AC is one of the most common ocular surface diseases, and T-helper type 2 (Th2) immune response is essential to coordinate the inflammatory response related to this disease Omega-3 fatty acids in diet can alleviate the symptoms of early and late allergic conjunctivitis (AC) through their anti-inflammatory activity, according to a study conducted by the University of Shuntian, Japan However, the role of lipid mediators in the pathogenesis and progression of AC has not been fully studied In addition, although omega-3 fatty acids have previously been found to be beneficial in patients with asthma or atopic dermatitis, the underlying mechanism is still unclear The researchers conducted an experiment (http:// to feed mice a diet rich in omega-3 and omega-6 fatty acids The researchers fed 4-week-old female rats omega-3 and omega-6 fatty acids for two months, and carried out two sensitization experiments, the first was after 30 days, the second was after 14 days From the 26th day to the 29th day, half of the mice in each group received eye drops containing 2mg of ragweed pollen, 10ml of PBS in the eye drops, and 10ml of PBS in the other mice, 2mg of ragweed pollen in the eye drops Then, 24 hours after the last eyedrop, the researchers evaluated the eye, eyelid, and conjunctival tissues of the mice The researchers observed that omega-3 fatty acids completely inhibited scratching around the eyes of mice, an allergic reaction to AC related itching.