echemi logo
  • Product
  • Supplier
  • Inquiry
    Home > Food News > Nutrition News > Omicron variants: BA.2 may cause more severe disease?

    Omicron variants: BA.2 may cause more severe disease?

    • Last Update: 2022-04-30
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit

    Omega Variant: Could BA.

    Could an upgraded omicron cause more severe disease? New research sounds the alarm

    At present, European and American countries have gradually introduced epidemic prevention measures

    But a new Japanese study found that a new subvariant, BA.

    Japanese researchers published a research report on the preprinted version of "bioRxiv" on the 15th, saying that BA.

     This result has caught everyone's attention: since February this year, the number of BA.


     Previously, the academic community agreed that BA.

     Japanese researchers conducted hamster infection experiments for comparison

    The researchers found that the RNA load of BA.

    In contrast, ba .


     This suggests that BA.

    Post-infection 'herd immunity' may not be as effective

    The number of people with acquired immunity after infection is relatively large, which is one of the advantages of European and American countries

    As the predominant strain globally, BA.

    1 convalescent serum showed strong antiviral effect on BA.
    1 strain, but the effect on BA.
    2 seemed to be poor, and its resistance to serum was 1.
    4 times that of BA.
    1 strain
    The researchers repeated the experiment in mice and came to similar conclusions:

    Compared with BA.
    1, the resistance of BA.
    2 to hamster serum was significantly increased by about 2.
    9 times during the recovery period of BA.
    1 infection

     The researchers also used the S protein of BA.
    1 to immunize mice to obtain antiserum, and used the mouse serum neutralization test.
    The results showed that the resistance of BA.
    2 to immune serum was 6.
    4 times that of BA.

    Not to mention those who were infected early in the pandemic

    Studies have shown that BA.
    2, like BA.
    1, is highly resistant to convalescent serum, whether it is the original strain Alpha or Delta

    A simple understanding is that it may not be as "safe" to face BA.
    2 as you might think, regardless of whether you have infected other mutants early or recently with BA.

    Do vaccines still work? What about antiviral drugs? In this regard, BA.
    2 continues the capabilities of BA.
    1 and seems to be slightly better

    Pseudovirus and vaccine-induced neutralizing antibody experiments showed that BA.
    2 was highly resistant to both mRNA and adenovirus vaccines
    In addition, BA.
    2 was almost completely resistant to two therapeutic monoclonal antibodies, Casirivimab and Imdevimab


    British scholars question the government: relaxation of epidemic prevention should provide scientific basis

    However, the mouse experiments cannot fully reflect the actual situation, and there are certain differences in the pathology and infection kinetics of the virus between humans and experimental animals

    Back in the real world, the evidence on the severity of BA.
    2 is mixed
    In countries where outbreaks have been contained, such as South Africa and the United Kingdom, hospitalizations continue to decline
    But in Denmark, where BA.
    2 has become a major source of infection, hospitalizations and deaths are rising

    This study is more of a wake-up call for us
    Deborah Fuller, a virologist at the University of Washington School of Medicine, believes that creating a system to specifically test for BA.
    2 will be the first thing many countries need to do


    Distinguishing BA.
    1 from BA.
    2 requires whole-genome sequencing, which is a relatively time-consuming and laborious process
    In a country where cases are growing in the tens of thousands, it is not easy to obtain relevant data and analyze it in a timely manner

    "Has the performance of humans surpassed the virus now?" Until the relevant data comes out, I don't think the epidemic prevention regulations can be lifted

    Penelope Tove, chairman of the British Medical Association's Public Health Medicine Branch, said recently that the number of confirmed cases in the UK is still high, with hundreds of people dying every day, but the UK has lifted epidemic prevention measures such as self-isolation
    "We have the right to question whether the government's decision is based on science

    Lawrence Young, a virologist at the University of Warwick, believes the pandemic is not over

    "If there's one thing we've learned over the past two years, it's that the impact and future of Covid-19 remains unpredictable," said Lawrence Young

    (Source: Internet, reference only)

    Labels: COVID-19ο

    This article is an English version of an article which is originally in the Chinese language on and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to with relevant evidence.