Oncogene: This combination therapy can effectively treat metastatic melanoma

Melanoma is a type of skin cancer characterized by the uncontrolled growth of pigment-producing cells located in the skin

Spanish researchers have recently discovered that the combination therapy of chemotherapy and BRAF inhibitors is a very effective strategy for the treatment of metastatic melanoma

Researchers from the Medical Institute of Del Mar Hospital and doctors from the Dermatology and Pathology Department of Del Mar Hospital participated in the study and analyzed the effect of the combination of two treatments on metastatic melanoma

The researchers tested the two individual therapies and combination therapies in mice and in vitro tumor cells

The co-corresponding author of the article, Dr.

This study also shows that low-dose chemotherapy (to avoid its toxicity), coupled with standard treatment with BRAF inhibitors, can have a huge impact on the progression of metastatic melanoma

The researchers also believe that this method can also be applied to other types of cancer, including some rare subtypes of melanoma, which are currently incurable due to the lack of BRAF gene mutations

Dr.

BRAF inhibitors are the gold standard method for the treatment of melanoma

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Alonso-Marañón, J.