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Today, Regeneron announced that its new crown neutralizing antibody combination therapy REGEN-COV (casirivimab+imdevimab) has reached the primary clinical endpoint in a phase 3 clinical trial for the prevention of new crown infection.
In the phase 3 clinical trial called 2069A, a total of 1,505 volunteers who were not infected by the new crown virus participated in the trial.
The results of the trial showed that a single dose of REGEN-COV reduced the participants' risk of developing symptomatic COVID-19 by 81% (p<0.
In a clinical trial called 2069B, 204 COVID-19 patients who tested positive for the new coronavirus but did not show symptoms received a dose of REGEN-COV or a placebo.
The results of the trial showed that a dose of REGEN-COV treatment reduced the risk of turning these asymptomatic patients into symptomatic COVID-19 patients by 31%, reaching the primary endpoint of the trial.
Note: The original text has been deleted
Reference materials:
Reference materials:[1] PHASE 3 PREVENTION TRIAL SHOWED 81% REDUCED RISK OF SYMPTOMATIC SARS-COV-2 INFECTIONS WITH SUBCUTANEOUS ADMINISTRATION OF REGEN-COV™ (CASIRIVIMAB WITH IMDEVIMAB).
[1] PHASE 3 PREVENTION TRIAL SHOWED 81% REDUCED RISK OF SYMPTOMATIC SARS-COV-2 INFECTIONS WITH SUBCUTANEOUS ADMINISTRATION OF REGEN-COV™ (CASIRIVIMAB WITH IMDEVIMAB).
[2] PHASE 3 TREATMENT TRIAL IN RECENTLY INFECTED ASYMPTOMATIC PATIENTS SHOWED REGEN-COV™ (CASIRIVIMAB WITH IMDEVIMAB) SIGNIFICANTLY REDUCED PROGRESSION TO SYMPTOMATIC COVID-19.
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