echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Drugs Articles > One flower and two lives: behind the battle between honeysuckle and honeysuckle

    One flower and two lives: behind the battle between honeysuckle and honeysuckle

    • Last Update: 2014-08-22
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com
    Author: Li early morning source: Ding Xiangyuan, 2014-08-22, 2000 edition Pharmacopoeia of the people's Republic of China, called honeysuckle flower bud and honeysuckle, but 2005 edition and 2010 Edition Pharmacopoeia of the people's Republic of China divided them into two items, honeysuckle and honeysuckle As a result, disputes arise On August 12, 2014, Lu Qun, deputy director of corruption prevention Office of Hunan Provincial Commission for Discipline Inspection, disclosed on his micro blog that a unscrupulous enterprise had spent a lot of money on public relations, revised the National Pharmacopoeia "turning honeysuckle into honeysuckle", and rumored that honeysuckle could cause "fire", causing heavy losses to tens of millions of flower farmers in the south, because of its Sina micro BLOG @ Royal historian on the way of 20 It's rare for more than 10000 fans and serving officials to publicly call for higher-level officials to take the blame and resign, so the microblog quickly attracted more attention After the first news on Weibo that a herbal tea could be "inflamed" by replacing honeysuckle with honeysuckle, many netizens exclaimed, "no wonder I was inflamed after drinking a herbal tea of so and so It turned out that they were not using honeysuckle but honeysuckle!" Because I always regard the saying of "getting angry" as a scientific slang When I write about "getting angry", I often criticize that the semantic meaning of the word is unclear Therefore, when some netizens make a exclamation, I just satirize in my heart Why does it lead to "getting angry" when no one points out the problem of the herbal tea? Later, it turned out that the incident was a masterpiece of a private media company after receiving money However, most netizens had already forgotten their "exclamation" at that time when Hunan Satellite TV news network revealed the origin and the background of the incident But in fact, even if there is no snitch from Hunan TV, we can easily find the "hard injury" of this rumor from the theory of traditional Chinese medicine Let's first look at what the Chinese Pharmacopoeia (2010 version) says: Honeysuckle: sweet and cold Return to lung, heart and stomach channel [function and indications] clear away heat and detoxify, evacuate wind heat It is used for bloated sores, larynx arthralgia, erysipelas, blood dysentery due to heat, febrile diseases and fever [1] Honeysuckle: sweet and cold Return to lung, heart, stomach channel [function and indications] clear away heat and detoxify, evacuate wind heat It is used for bloated sores, larynx arthralgia, erysipelas, blood dysentery with heat toxin, febrile diseases and fever [2] Why? Why is it the same! That is to say, whether the raw material of the herbal tea comes from honeysuckle or honeysuckle in theory, it will not lead to the so-called "fire", so why do a large number of netizens think they "fire" when there is news that the herbal tea will make people "fire"? It can be seen how absurd the so-called "burning" and "clearing fire" are, however, the natural development or psychological implication of some symptoms If the effect of "clearing fire" after drinking the herbal tea is accurate, how can this rumor easily spread and strike the male farmers who grow honeysuckle? Ironically, most of the audience of herbal tea agreed with the TCM system emotionally, but most of them didn't know what the TCM theory called, so they could only listen to the wind is the rain and follow the feeling On the contrary, people who were not the users of herbal tea could easily find out the absurdity of the rumor I noticed that at that time, these rational partners were mostly cynical about the news Of course, the main reason why we refuse the herbal tea is not honeysuckle or honeysuckle, but Prunella vulgaris with liver toxicity In 2005 and 2007, some people sued the seller and manufacturer of the herbal tea for containing the Chinese medicine ingredients of Prunella vulgaris and adding the drugs prohibited by the food hygiene law without authorization, but they were all rejected by the court In order to avoid outgrowth, we will continue to talk about honeysuckle and honeysuckle In fact, since the Chinese Pharmacopoeia revised the relevant terms of honeysuckle in 2005, the debate on honeysuckle and honeysuckle has not stopped no matter in academia or in the folk Before Lu Qun's microblog bombardment, many media had relevant reports For example, on July 7, 2014, Qianxinan Daily reported the rise and fall of local honeysuckle industry due to the change of Pharmacopoeia entry, with the title of "the same blossom, two destinies, honeysuckle becomes" sad flower " In terms of academic research, it is found that many scholars in the field of traditional Chinese medicine believe that "honeysuckle is significantly lower in sales price, so when preparing the medicine containing honeysuckle, some illegal traders often use honeysuckle to replace honeysuckle for profit, which has an adverse impact on the health of patients [3] ”However, what kind of adverse effects on the health of patients is unclear If as like as two peas in the People's Republic of China Pharmacopoeia, they are similar in their tropism to the function and the main function, but they are different in chemical composition (it can be seen that the chemical composition of Chinese medicine can also be analyzed Some people do not think that Chinese medicine system can not be evaluated by Western Science): the dried honeysuckle dry products contain chlorogenic acid (C16H18O9) not less than 1.5% The content of luteolin (c21h20o11) shall not be less than 0.050%, chlorogenic acid (c16h18o9) shall not be less than 2.0%, and the total content of Lonicera cinerea saponin B (c65h106o32) and Dipsacus aspectus saponin B (c53h86o22) shall not be less than 5.0% However, it is not known whether the difference in chemical composition can lead to the difference in therapeutic effect The limited pharmacological research can only indicate that in vitro experiments, the substances of honeysuckle and honeysuckle have certain effects on "antibacterial, antiviral, anti-inflammatory, liver and gall [4] ”In the world, tens of millions of so-called "drugs" can achieve the above effects in experiments outside the human body, but most of them fail in rigorous clinical trials However, in China, due to the special national conditions and history, this kind of traditional Chinese medicine has been widely used in the Chinese people for a long time, such as jianerqingjieye, Weic Yinqiao tablet, which is claimed to be able to prevent the new type A H1N1 Although Li Lianda, academician of the Chinese Academy of engineering and chief scientist of the Chinese Academy of traditional Chinese medicine, thinks that "honeysuckle and honeysuckle are commonly used Chinese herbal medicines for clearing away heat and detoxifying, are important Chinese herbal medicines for treating infectious diseases, infectious diseases and various emerging viral diseases, are very effective and safe Chinese herbal medicines, and are indispensable Chinese herbal medicines in clinical practice " But in fact, the achievements of traditional Chinese medicine in the war on infectious diseases in the history are very poor [5] If it is not combined with the diagnosis and treatment measures of modern medicine, traditional Chinese medicine has almost no use in the war on most diseases (self limited diseases are another topic) Taking Weic Yinqiao tablet as an example, if three Western medicines, chlorphenamine maleate, paracetamol and vitamin C, were not added to the traditional Chinese patent medicine "Yinqiao Powder", how could it play a significant antipyretic and analgesic effect? If you have confidence in the efficacy of Yinqiao Powder, why do you need to pull western medicine to help the battle? In addition, it should be noted that the addition of vitamin C to the drug actually stems from a traditional misunderstanding in western medicine Many early western medicine textbooks mentioned that vitamin C has an effect on the treatment of the common cold, but a large number of evidence-based medical evidence suggests that the use of vitamin C after the onset of cold symptoms Compared with placebo, there is no significant difference in the control of the duration and severity of the common cold Therefore, the role of vitamin C in the treatment of the common cold is no longer mentioned in the newer textbooks However, the response of VEC Yinqiao Tablets in China is very good Do these drug users know what ingredients really work? Has a large amount of evidence proved that the invalid vitamin C can become effective as soon as it is put on the vest of traditional Chinese medicine? It should be said that the reason why the public pays attention to honeysuckle this time has nothing to do with medicine Probably, it is hoped that Lu Qun, a cadre of the Commission for Discipline Inspection, will report the real name of high-level officials and achieve anti-corruption results But I'm more concerned about whether the State Food and drug administration is willing to clarify the confusion of the public Should honeysuckle be distinguished from honeysuckle? In addition to the above differences in chemical composition, in the end, can they replace each other in the treatment? With 2005 as the dividing point, what benefits would it bring to the public if the traditional Chinese medicine and drug dealers could strictly distinguish honeysuckle from honeysuckle? Can the FDA answer these questions? I would venture to put forward a rough plan here, which may end the dispute between honeysuckle and honeysuckle Since honeysuckle as like as two peas, the Chinese medicine community still needs to distinguish between the two Logically, there is only one reason why there is difference in the efficacy between the two How can we evaluate this difference? We might as well design a clinical trial plan carefully: divide the patients into several groups and start to receive treatment at the same time Each group of patients should suffer from the same disease According to the syndrome differentiation of traditional Chinese medicine, the severity, development stage and physical condition of the disease are basically similar In order to eliminate the artificial test error, except for the data analysis personnel, neither the doctor nor the tested patients know how to take it Whether the drug used contains honeysuckle or honeysuckle or placebo without any traditional Chinese medicine or other pharmaceutical ingredients After the test, the results will be released to the public There may be three results: first, the drug containing honeysuckle is better than the drug containing honeysuckle, both of which are better than placebo; second, the drug containing honeysuckle is better than the drug containing honeysuckle, both of which are better than placebo; third, there is no difference between the two, but both are better than placebo If the first two situations occur, it is of practical significance to distinguish honeysuckle and honeysuckle strictly I believe that the scholars of the national pharmacopoeia committee, who dominate the renewal of the Pharmacopoeia entries, are more inclined to believe the first situation in their hearts Otherwise, it will not cause serious damage to the economic interests of the farmers who planted large quantities of honeysuckle in the south, and the non-governmental people and advocates including the land group do not have to If we want to distinguish the two scholars, we will hope for a third situation (the second situation belongs to the counter attack of honeysuckle It seems that all parties have no such claim Even the Southern farmers who grow honeysuckle hope that honeysuckle and honeysuckle are equal.) But what kind of results will appear? We can only judge through this test We have been arguing with each other for years Why not compete in a strict clinical trial? After all, gold is not afraid of fire If you all have confidence in your opinions, it's not difficult to promote such a clinical trial Why did you quarrel for nearly ten years without any result? The only reason I can think of is that the fourth situation is the most likely to occur in the above-mentioned trials: both are not superior to placebo in terms of treatment - this is equivalent to declaring the death penalty of both Chinese medicines at the same time In any case, neither side wants to have the outcome of both sides' failure Therefore, their argument can only be separated from science They can use the political and economic forces they have to fight for real gold and silver The most concerned scientific issue of individual people will still be chicken feathers References: 1 Compiled by the National Pharmacopoeia Committee Chinese
    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.